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Association of midtrimester short femur and short humerus with fetal growth restriction.
MedLine Citation:
PMID:  23192722     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To investigate the association between the midtrimester presence of short femur and short humerus and intrauterine growth restriction. METHODS: This retrospective study included ultrasound examinations of 1043 fetuses. Fetuses with normal-length bones were compared with fetuses that had femoral or humeral lengths below the 5(th) percentile for gestational age by Student's t-test and the chi-squared test. The association between short bones and fetal growth restriction development was evaluated by Fisher's exact test. Fetuses with estimated weight below the 10(th) percentile for gestational age and abnormal umbilical artery flow were considered to have growth restriction. RESULTS: Femoral and humeral lengths were normal in 974 (93.4%) fetuses; 19 (1.8%) fetuses had short femora, 65 (6.2%) had short humeri, and 15 (1.4%) had short femora and humeri combined. Of fetuses included in the analysis, 603 (57.8%) underwent Doppler examination. Short femur [odds ratio = 9.7, 95% confidence interval = 1.9-50.2, P = 0.03] and short humerus (odds ratio = 13, 95% confidence interval = 4.9-34.6, P < 0.001) were associated with fetal growth restriction. CONCLUSION: Fetuses with midtrimester short femur, short humerus, or short femur and humerus combined require more intensive surveillance for growth restriction development. © 2012 John Wiley & Sons, Ltd.
Authors:
Ana Alice Vidal de Carvalho; José Antônio Carvalho; Israel Figueiredo; Luis Guillermo Coca Velarde; Edson Marchiori
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-28
Journal Detail:
Title:  Prenatal diagnosis     Volume:  -     ISSN:  1097-0223     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-4     Citation Subset:  -    
Copyright Information:
© 2012 John Wiley & Sons, Ltd.
Affiliation:
Department of Radiology, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil; Hospital Universitário Antônio Pedro, Departamento de Radiologia. Centro, Niterói, Rio de Janeiro, Brazil.
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