Document Detail

Association of length of stay and total hospital charges with antimicrobial regimen changes.
MedLine Citation:
PMID:  3132038     Owner:  NLM     Status:  MEDLINE    
The association of changes in antimicrobial therapy with length of stay and total hospital charges in a 600-bed general medical hospital was studied. Changes in antimicrobial regimens were examined in three diagnosis-related groups (DRGs): DRG 79 (respiratory infections and inflammations, age greater than 69 years, and/or secondary diagnosis), DRG 89 (simple pneumonia and pleurisy, age greater than 69 years, and/or secondary diagnosis), and DRG 416 (septicemia, age greater than 17 years). These changes were defined as follows: (1) switching from one drug or drug combination to another, (2) adding one or more drugs to a regimen, or (3) discontinuing one drug of a multiple-drug regimen. Variables examined for association with these changes were length of hospital stay and pharmacy, antimicrobial, intravenous therapy, and hospital charges. In DRGs 79 and 89, changes in antimicrobial regimens were associated with significantly longer hospital stay and significantly higher pharmacy, antimicrobial, intravenous therapy, and total hospital charges. In DRG 416, changes in antimicrobial regimens were not associated with higher charges or longer stay. Significant differences among DRGs were found with respect to the types of changes, with more changes from broad- to narrow-spectrum coverage occurring in DRGs 89 and 416 than in DRG 79. At this institution, patients whose antimicrobial regimens were changed had significantly longer hospital stays and higher charges in two of three DRGs.
D W Raisch; J L Bootman; W F McGhan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of hospital pharmacy     Volume:  45     ISSN:  0002-9289     ISO Abbreviation:  Am J Hosp Pharm     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-07-14     Completed Date:  1988-07-14     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370474     Medline TA:  Am J Hosp Pharm     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  819-23     Citation Subset:  IM    
Department of Pharmacy Practice, College of Pharmacy, University of Arizona, Tucson 85721.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use
Anti-Infective Agents / therapeutic use*
Diagnosis-Related Groups / economics
Fees and Charges
Hospital Bed Capacity, 500 and over
Hospitalization / economics*
Length of Stay*
Pharmacy Service, Hospital / economics
Statistics as Topic
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Anti-Infective Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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