Document Detail

Association of kisspeptin-10 levels with abortus imminens: a preliminary study.
MedLine Citation:
PMID:  21847585     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To investigate the association between kisspeptin 10 (Kp-10) levels and early pregnancy bleeding and perinatal outcome.
METHODS: A total of 20 pregnant women with the complaint of vaginal bleeding during 7-18 gestational weeks and 20 healthy gestational week matched pregnant women were included in the study. Maternal plasma Kp-10 levels were measured with the enzyme immunoassay method. Adverse pregnancy outcomes like intrauterine growth restriction, preterm delivery, preeclampsia and low birth weight were evaluated in both groups.
RESULTS: Maternal plasma Kp-10 levels (p = 0.01) and birth weight (p = 0.06) were found to be lower in women with bleeding. Intrauterine growth restriction, preterm delivery and intrauterine exitus were noted more commonly in women with bleeding (10 vs. 0%, 25 vs. 15% and 20 vs. 0%, p = 0.08). Preeclampsia were developed in 5% of both groups. Kp-10 levels showed positive correlation with gestational week (p = 0.02) and ALT levels (p = 0.02).
CONCLUSION: [corrected] Kp-10 levels were found lower in women with early pregnancy bleeding.
Serif Kavvasoglu; Zehra Sema Ozkan; Banu Kumbak; Mehmet Sımsek; Necip Ilhan
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-08-17
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  285     ISSN:  1432-0711     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-02-13     Completed Date:  2012-07-02     Revised Date:  2014-10-20    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  649-53     Citation Subset:  IM    
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MeSH Terms
Abortion, Threatened / blood*
Alanine Transaminase / blood
Fetal Growth Retardation / blood
Infant, Low Birth Weight
Infant, Newborn
Kisspeptins / blood*
Pre-Eclampsia / blood
Pregnancy Outcome
Premature Birth / blood
Uterine Hemorrhage / blood
Young Adult
Reg. No./Substance:
0/KISS1 protein, human; 0/Kisspeptins; EC Transaminase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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