Document Detail

Association of inflammatory markers with angiographic severity and extent of coronary artery disease.
MedLine Citation:
PMID:  19264307     Owner:  NLM     Status:  MEDLINE    
Inflammatory processes play a pivotal role in the pathogenesis of atherosclerosis and mediate many of the stages of atheroma development, from initial leukocyte recruitment to eventual rupture of the unstable atherosclerotic plaque. Several systemic inflammatory markers reflect different degrees of inflammation and have been indicated as independent risk factors in cardiovascular disease, especially in unstable coronary syndromes. However, whether elevated levels of circulating inflammatory markers play a role in the extent and severity of atherosclerosis remains controversial. The present review summarizes our current understanding of the relationship between inflammatory markers and the presence and extent of coronary atherosclerosis, in order to assess the potential utility of these markers in identifying patients with higher levels of atherosclerotic burden.
Maria Drakopoulou; Konstantinos Toutouzas; Elli Stefanadi; Eleftherios Tsiamis; Dimitris Tousoulis; Christodoulos Stefanadis
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-02-07
Journal Detail:
Title:  Atherosclerosis     Volume:  206     ISSN:  1879-1484     ISO Abbreviation:  Atherosclerosis     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-05     Completed Date:  2009-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0242543     Medline TA:  Atherosclerosis     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  335-9     Citation Subset:  IM    
1st Department of Cardiology, Medical School of Athens University, Hippokration Hospital, Athens, Greece.
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MeSH Terms
Biological Markers / analysis*
C-Reactive Protein / analysis
Coronary Angiography
Coronary Artery Disease / complications*
Inflammation / complications*
Reg. No./Substance:
0/Biological Markers; 9007-41-4/C-Reactive Protein

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