Document Detail

Association of higher adiposity and wheezing in infants with lower respiratory illnesses.
MedLine Citation:
PMID:  20219024     Owner:  NLM     Status:  MEDLINE    
AIM: The incidences of asthma and obesity have been steadily increasing over the past two decades, with several studies showing a relationship between these conditions. We investigated the influence of higher weight for height (WFH) Z-score on wheezing in infants with lower respiratory tract infections (LRTI).
METHODS: We reviewed the medical charts of all infants younger than l year of age who were admitted with the first episode of LRTI between 2000 and 2008. Subjects were classified into six groups according to WFH Z-score.
RESULTS: Wheezing was more frequent in infants with higher WFH Z-scores. Especially, wheezing infants aged 3-6 months and 6-9 months had significantly higher WFH Z-scores than had their non-wheezing counterparts (p = 0.05 and p < 0.01 respectively). Multivariate logistic regression showed that age (OR = 0.76, p < 0.001), male gender (OR = 1.61, p = 0.005) and WFH Z-score (OR = 1.12, p = 0.007) were independently associated with wheezing.
CONCLUSION:   In this study we could show that a higher WFH Z-score was independently associated with wheezing in infancy. Attainment of appropriate weight for age may reduce the risk of wheezing in infants with respiratory diseases.
Hye Mi Jee; Hyun Kyong Seo; Se Eun Hyun; Eun Gyong Yoo; Cheol Hong Kim; Man Yong Han
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  99     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-10-12     Completed Date:  2011-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  1365-9     Citation Subset:  IM    
Copyright Information:
© 2010 The Author(s)/Journal Compilation © 2010 Foundation Acta Paediatrica.
Department of Pediatrics, CHA Bundang Medical Center, CHA University, Bundang-gu, Seongnam-si, Gyeonggi-do, Korea.
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MeSH Terms
Asthma / epidemiology
Logistic Models
Multivariate Analysis
Obesity / epidemiology*
Republic of Korea / epidemiology
Respiratory Sounds* / etiology,  immunology
Respiratory Tract Diseases / epidemiology*
Retrospective Studies
Weight Gain

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