Document Detail

Association of height with outcomes in patients with acute myocardial infarction receiving reperfusion therapy.
MedLine Citation:
PMID:  15904648     Owner:  NLM     Status:  MEDLINE    
Data were evaluated for patients with acute ST-elevation myocardial infarction (n = 94,182) enrolled in 6 large clinical trials evaluating the efficacy of various reperfusion strategies. It was found that compared with the tallest quartile, incidences of in-hospital reinfarction, stroke, major bleeding, cardiogenic shock, heart failure, and death in the shortest group were 1.4, 1.7, 1.7, 1.8, 1.9, and 2.4 times greater, respectively. Although a strong inverse association of height was observed with unadjusted 30-day mortality (p <0.001), it was attenuated after adjustment for confounders, including weight, and appeared to be nonlinear, such that for height </=165 cm, the odds ratio [OR] for a 10-cm increment in height was 1.115 (95% confidence interval [CI] 1.014 to 1.223) and for height >165 cm, the OR for a 10-cm increase in height was 0.962 (95% CI 0.896 to 1.033). These data indicate that height-related differences in 30-day mortality are explained in large part by height-related differences in patients' clinical characteristics.
Rajendra H Mehta; Robert M Califf; Jyotsna Garg; Karen S Pieper; John H Alexander; David J Moliterno; Frans Van de Werf; E Magnus Ohman; Harvey D White; Eric J Topol; Christopher B Granger
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  95     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-05-20     Completed Date:  2005-07-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1371-5     Citation Subset:  AIM; IM    
Duke Clinical Research Institute, Durham, North Carolina, USA.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary
Body Height*
Body Weight
Middle Aged
Myocardial Infarction / mortality*,  therapy
Randomized Controlled Trials as Topic
Thrombolytic Therapy

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