| Association of heart rate recovery and maximum oxygen consumption in patients with chronic congestive heart failure. | |
| | |
MedLine Citation:
|
PMID: 16890115 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Peak oxygen consumption (peak VO2) is one of the strongest predictors of mortality in patients with congestive heart failure (CHF). In contrast to measurements of peak VO2, which requires analysis of expired gases, heart rate recovery, defined as maximum heart rate minus heart rate at 1 minute after exercise, is easily obtained. The current study was undertaken to determine the association between peak VO2 and heart rate recovery in patients with CHF. METHODS: Retrospective data on VO2 and heart rate recovery were analyzed in 296 patients with CHF secondary to left ventricular systolic dysfunction (left ventricular ejection fraction [LVEF] <50%) who had undergone cardiopulmonary exercise testing (CPET). Patients exercised on a treadmill using a graded work rate protocol with the work increasing to a symptom-limited maximum. Peak oxygen consumption was defined as the highest value of oxygen uptake attained in the final 20 seconds of exercise when the respiratory exchange ratio was >1.0. RESULTS: Heart rate recovery and peak VO2 correlated moderately (r = 0.47, p < 0.001). The degree of correlation was similar in patients receiving beta-blockers (r = 0.47, p < 0.001) and those not receiving beta-blockers (r = 0.49, p < 0.001). CONCLUSIONS: Although heart rate recovery and peak VO2 correlated moderately, from a clinical standpoint, this finding is probably not strong enough to use heart rate recovery in lieu of peak VO2. This modest correlation of two independent predictors of outcome may suggest their usefulness when combined in a multivariate score. |
| | |
Authors:
|
David S Hirsh; Timothy J Vittorio; Svetlana L Barbarash; Alhakam Hudaihed; Chi-Hong Tseng; Allison Arwady; Rochelle L Goldsmith; Ulrich P Jorde |
Related Documents
:
|
19101855 - Exercise training in older patients with systolic heart failure: adherence, exercise ca... 15809365 - Antioxidative effects of exercise training in patients with chronic heart failure: incr... 12943875 - Effects of cold exposure on submaximal exercise performance and adrenergic activation i... 17996825 - Exercise-induced increases in oxidized low-density lipoprotein are associated with adve... 18360045 - Patients with a hypertensive response to exercise have impaired left ventricular diasto... 10482675 - The generation of active oxygen species differs in tobacco and grapevine mesophyll prot... |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural Date: 2006-07-10 |
Journal Detail:
|
Title: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Volume: 25 ISSN: 1557-3117 ISO Abbreviation: J. Heart Lung Transplant. Publication Date: 2006 Aug |
Date Detail:
|
Created Date: 2006-08-07 Completed Date: 2006-10-24 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9102703 Medline TA: J Heart Lung Transplant Country: United States |
Other Details:
|
Languages: eng Pagination: 942-5 Citation Subset: IM |
Affiliation:
|
Heart Failure Program, New York University School of Medicine, New York, New York 10016, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Chronic Disease Female Heart Failure / metabolism*, physiopathology* Heart Rate* Humans Male Middle Aged Oxygen / metabolism* Retrospective Studies |
| Grant Support | |
ID/Acronym/Agency:
|
K23 HL04381/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
|
7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Similar efficacy and safety of enteric-coated mycophenolate sodium (EC-MPS, myfortic) compared with ...
Next Document: Grafting an acellular 3-dimensional collagen scaffold onto a non-transmural infarcted myocardium ind...