| Association of electrocardiographic changes with severity of coronary artery disease and short term outcome in patients with non-ST-segment elevation acute coronary syndromes. | |
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MedLine Citation:
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PMID: 20383417 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess the association between electrocardiogram (ECG) changes in non-ST-segment elevation acute coronary syndrome (NSTE- ACS) patients with severity of coronary artery disease (CAD) and short-term outcome. METHODS: In this cross-sectional descriptive-analytical study, 111 patients admitted to the Cardiology Department of Shahid Madani Heart Hospital, Tabriz, Iran between March 2005 and March 2007 with first NSTE-ACS, and had undergone coronary angiography during index event were evaluated. RESULTS: One hundred and eleven patients (64 males, and 47 females) were enrolled, and their in-hospital and short-term outcome with a mean follow-up period of 4.6 +/- 1.8 months was evaluated. Patients with ST-T changes on admission had higher rates of death (16.7 versus 2.7%, p=0.01), recurrent angina (36.1 versus 6.7%, p=0.001), and pulmonary edema (8.3 versus 1.3%, p=0.045). The mean left ventricular ejection fraction (LVEF) of patients with ECG changes were significantly lower than those without ECG changes (p=0.001). Mitral regurgitation (MR) was also more common among those with ECG changes (p=0.006). In a multivariate regression analysis, the only independent predictor of short-term mortality and adverse clinical event was ST depression on ECG (p=0.001). CONCLUSION: In patients with first NSTE-ACS, ST deviation is associated with adverse short-term outcome including more severe CAD, lower LVEF, and more common MR. |
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Authors:
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Samad Ghaffari; Ahmad Separham; Leili Pourafkari |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Saudi medical journal Volume: 31 ISSN: 0379-5284 ISO Abbreviation: Saudi Med J Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-12 Completed Date: 2010-08-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7909441 Medline TA: Saudi Med J Country: Saudi Arabia |
Other Details:
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Languages: eng Pagination: 400-5 Citation Subset: IM |
Affiliation:
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Cardiology Department, Shahid Madani Heart Hospital, Daneshgah St., Postal Code 5166615573, Tabriz, Iran. ghafaris@gmail.com |
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Coronary Syndrome
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diagnosis* Case-Control Studies Coronary Disease / diagnosis* Cross-Sectional Studies Electrocardiography* Female Humans Iran Male Middle Aged Prognosis Severity of Illness Index* |
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