Document Detail

Association of dietary omega-3 fatty acids with prevalence of metabolic syndrome: The National Heart, Lung, and Blood Institute Family Heart Study.
MedLine Citation:
PMID:  23711994     Owner:  NLM     Status:  Publisher    
BACKGROUND & AIMS: Metabolic syndrome (MetS), characterized by abdominal obesity, atherogenic dyslipidemia, elevated blood pressure, and insulin resistance is a major public health concern in the United States. Omega-3 fatty acids have been relatively well studied in relation to many individual cardiovascular risk factors; however, their effects on MetS are not well established. METHODS: We conducted a cross-sectional study consisting of 4941 participants from the National Heart, Lung, and Blood Institute (NHLBI) Family Heart Study to assess the relation of dietary omega-3 fatty acids with the prevalence of MetS. Omega-3 intake was assessed using a food frequency questionnaire and we used generalized estimating equations to estimate adjusted odds ratios for prevalent MetS. RESULTS: Our study population had a mean age (SD) of 52.1 (13.9) years and 45.9% were men. The mean (SD) of dietary omega-3 fatty acids was 0.25 g/day (0.27). From the lowest to the highest quintile of dietary omega-3 fatty acids, multivariable adjusted ORs (95% CI) for MetS were 1.00 (ref), 0.90 (0.72-1.13), 1.03 (0.82-1.28), 0.94 (0.74-1.18), and 0.99 (0.77-1.25), respectively. In a secondary analysis, neither fish consumption nor dietary alpha-linolenic acid was associated with MetS. CONCLUSIONS: Our findings do not support an association between dietary omega-3 fatty acids and MetS in a large US population.
Y H Lana Lai; Andrew B Petrone; James S Pankow; Donna K Arnett; Kari E North; R Curtis Ellison; Steven C Hunt; Luc Djoussé
Related Documents :
458264 - Reverse cross-coupling in the synthesis 3 alpha, 7 alpha-dihydroxy-5 beta-cholestanoic ...
8555404 - Fourier-transform ion cyclotron resonance mass spectrometric evidence for the formation...
1632524 - Hydrophobic interaction chromatography fractionates lipoteichoic acid according to the ...
7014484 - Synthesis of the dodecapeptide-alpha mating factor of saccharomyces cerevisiae.
3210074 - Influence of different dietary fats on the incorporation of exogenous fatty acids into ...
1199614 - Studies on the synthesis of liver phospholipids and the turnover of plasma phospholipid...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-5-9
Journal Detail:
Title:  Clinical nutrition (Edinburgh, Scotland)     Volume:  -     ISSN:  1532-1983     ISO Abbreviation:  Clin Nutr     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-5-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309603     Medline TA:  Clin Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013. Published by Elsevier Ltd.
Boston University School of Medicine, Boston, MA, USA; Clinical Research Center, Sarawak General Hospital, Kuching, Malaysia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Use of Allosteric Targets in the Discovery of Safer Drugs.
Next Document:  Human mannose-binding lectin 2 is directly regulated by peroxisome proliferator-activated receptors ...