| Association of coronary plaque composition and arterial remodelling: A optical coherence tomography study. | |
| | |
MedLine Citation:
|
PMID: 22341594 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
BACKGROUND: Conflicting data have been reported about the association between plaque composition and remodelling index (RI). The aim of this study is to evaluate the relationship between plaque morphology obtained by optical coherence tomography (OCT) and arterial remodelling. METHODS AND RESULTS: OCT and intravascular ultrasound imaging pull back was performed at corresponding sites on 94 lesions in 47 patients. OCT plaque characteristics for lipid content, fibrous cap thickness, thin-cap fibroatheroma (TCFA), plaque rupture, thrombus, calcification and erosion were derived using validated criteria. Compared with intermediate/negative remodelling (RI<1.0), positive remodelling (RI>1.0) was associated with presence of higher lipid pool (2.86±0.42 vs. 2.20±0.78; p<0.001), thin fibrous cap (47.86±25.43μm vs. 74.41±32.41μm; p<0.001), TCFA>3mm (82.1% vs. 22.7%; p<0.0001), plaque rupture and thrombus (42.8% vs. 19.7%; p=0.024), and higher plaque burden (73.70 vs. 70.70; p=0.048). No difference was observed in the presence of calcification and plaque erosions. CONCLUSIONS: Coronary lesions with positive remodelling show higher incidences of vulnerable plaque and plaque rupture across the lesion length. This potentially explains the correlation between unstable coronary syndromes and positive remodelling. |
| | |
Authors:
|
Sudhir Rathore; Mitsuyasu Terashima; Hitoshi Matsuo; Yoshihisa Kinoshita; Masashi Kimura; Etsuo Tsuchikane; Kenya Nasu; Mariko Ehara; Yasushi Asakura; Osamu Katoh; Takahiko Suzuki |
Related Documents
:
|
6742784 - Nonhemorrhagic venous infarction of the spinal cord. 9921864 - Visual symptoms with dural arteriovenous malformations draining into occipital veins. 3168684 - Pharmacoangiographic diagnosis of venous invasion of carcinoma of the colon with refere... 23247114 - A prospective randomised longitudinal study involving 6-months of endurance or resistan... 22041664 - Study of the ascending lumbar and iliolumbar veins: surgical anatomy, clinical implicat... 19267154 - Endovascular treatment of ruptured abdominal aneurysm into the inferior vena cava in pa... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-10-20 |
Journal Detail:
|
Title: Atherosclerosis Volume: - ISSN: 1879-1484 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
|
Created Date: 2012-2-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0242543 Medline TA: Atherosclerosis Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
|
Department of Cardiology, St George's Hospital, Blackshaw Road, Tooting, London, UK; Department of Cardiology, Toyohashi Heart Center, 21-1, Gobudori, Oyama-cho, Toyohashi 441-8530, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Selective improvement in renal function preserved remote myocardial microvascular integrity and arch...
Next Document: High serum total cholesterol levels is a risk factor of ischemic stroke for general Japanese populat...