Document Detail


Association of condylomas with intraepithelial and microinvasive cervical neoplasia: histopathology of conization and hysterectomy specimens.
MedLine Citation:
PMID:  6327546     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The tissues for 110 patients who received conization and/or hysterectomy following colposcopic evaluation for abnormal Pap smears were evaluated in a blind, retrospective fashion. The patients were grouped as condyloma only, dysplasia, carcinoma in situ, and microinvasion. Special note was taken of the presence of condyloma in those patients with dysplasia or greater. The mean age for each group was determined, and the significance of the differences between groups was assessed using Student's t test. Eighty-three (75%) patients showed evidence of condyloma in at least one section. The mean age of 33.0 years for this group was significantly lower (p less than 0.01). Despite the possibility that condylomas may represent a venereal infection unrelated to carcinogenesis, the association of condylomas and cervical intraepithelial neoplasia is strong. The findings in this study are consistent with the hypothesis that some forms of dysplasia represent a virally transformed epithelium.
Authors:
R E Zuna
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists     Volume:  2     ISSN:  0277-1691     ISO Abbreviation:  Int. J. Gynecol. Pathol.     Publication Date:  1984  
Date Detail:
Created Date:  1984-07-02     Completed Date:  1984-07-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8214845     Medline TA:  Int J Gynecol Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  364-72     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Animals
Carcinoma in Situ / etiology,  pathology
Condylomata Acuminata / etiology,  pathology*
Female
Humans
Middle Aged
Papillomaviridae
Tumor Virus Infections / complications
Uterine Cervical Dysplasia / etiology,  pathology*
Uterine Cervical Neoplasms / etiology,  pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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