Document Detail

Association of cervical internal carotid artery aneurysm with ipsilateral vertebrobasilar aneurysm in two children: a segmental entity?
MedLine Citation:
PMID:  17384955     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: A combination of cervical and intradural aneurysm in children in the absence of systemic disorders has previously not been reported. CASE REPORT: We report two boys with an identical combination of fusiform cervical internal carotid aneurysm and ipsilaterally located vertebrobasilar aneurysm. They had no history of trauma, they did not display any personal or familial signs of systemic disease, and the testing for collagen disease was negative. The location and appearance of the aneurysms and the identical anatomical disposition in the patients indicated a non-randomly distributed segmental vulnerability. CONCLUSION: The cases demonstrate primary morphological signs of a developmental error being expressed in two seemingly separate segments but linked by the hypoglossal artery. It suggests a segmental error related to this embryonic vessel. They also show that few phenotypes are specific for a genotypic disorder and highlight the importance of analysing different etiologies for aneurysm formation and anatomical disposition when taking treatment strategy decisions.
S Holmin; A Ozanne; W Y Zhao; H Alvarez; T Krings; P Lasjaunias
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-03-24
Journal Detail:
Title:  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery     Volume:  23     ISSN:  0256-7040     ISO Abbreviation:  Childs Nerv Syst     Publication Date:  2007 Jul 
Date Detail:
Created Date:  2007-05-24     Completed Date:  2007-10-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8503227     Medline TA:  Childs Nerv Syst     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  791-8     Citation Subset:  IM    
Service de Neuroradiologie Diagnostique et Thérapeutique, Hôpital de Bicêtre, 78 Rue du Général Leclerc, 94275, Le Kremlin-Bicêtre, France.
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MeSH Terms
Aneurysm / diagnosis*,  surgery
Basilar Artery / embryology,  pathology*,  surgery
Carotid Artery Diseases / complications*,  surgery
Carotid Artery, Internal / embryology,  pathology*,  surgery
Cerebellum / blood supply
Cervical Vertebrae
Intracranial Aneurysm / complications*,  surgery
Treatment Outcome
Vertebral Artery / embryology,  pathology*,  surgery

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