| Association between white-coat effect and blunted dipping of nocturnal blood pressure. | |
| | |
MedLine Citation:
|
PMID: 19629048 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: In this study, we assessed whether the white-coat effect (difference between office and daytime blood pressure (BP)) is associated with nondipping (absence of BP decrease at night). METHODS: Data were available in 371 individuals of African descent from 74 families selected from a population-based hypertension register in the Seychelles Islands and in 295 Caucasian individuals randomly selected from a population-based study in Switzerland. We used standard multiple linear regression in the Swiss data and generalized estimating equations to account for familial correlations in the Seychelles data. RESULTS: The prevalence of systolic and diastolic nondipping (<10% nocturnal BP decrease) and white-coat hypertension (WCH) was respectively 51, 46, and 4% in blacks and 33, 37, and 7% in whites. When white coat effect and nocturnal dipping were taken as continuous variables (mm Hg), systolic (SBP) and diastolic BP (DBP) dipping were associated inversely and independently with white-coat effect (P < 0.05) in both populations. Analogously, the difference between office and daytime heart rate was inversely associated with the difference between daytime and night-time heart rate in the two populations. These results did not change after adjustment for potential confounders. CONCLUSIONS: The white-coat effect is associated with BP nondipping. The similar associations between office-daytime values and daytime-night-time values for both BP and heart rate suggest that the sympathetic nervous system might play a role. Our findings also further stress the interest, for clinicians, of assessing the presence of a white-coat effect as a means to further identify patients at increased cardiovascular risk and guide treatment accordingly. |
| | |
Authors:
|
Murielle Bochud; Pascal Bovet; Peter Vollenweider; Marc Maillard; Fred Paccaud; Gilles Wandeler; Anne Gabriel; Michel Burnier |
Related Documents
:
|
2249378 - Combined alpha/beta-blockade versus beta 1-selective blockade in essential hypertension... 21449898 - Providing peep during neonatal resuscitation: which device is best? 2657078 - Management of essential hypertension in the black patient: profiling as the initial app... 10223778 - Impaired endothelial-dependent forearm vascular relaxation in black americans. 2488758 - Vasopressin-induced changes in permeability of peritoneal mesothelium for urea "in vitro". 7294338 - Epidural space pressures during pregnancy. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-07-23 |
Journal Detail:
|
Title: American journal of hypertension Volume: 22 ISSN: 1941-7225 ISO Abbreviation: Am. J. Hypertens. Publication Date: 2009 Oct |
Date Detail:
|
Created Date: 2009-09-24 Completed Date: 2010-01-14 Revised Date: 2011-06-30 |
Medline Journal Info:
|
Nlm Unique ID: 8803676 Medline TA: Am J Hypertens Country: United States |
Other Details:
|
Languages: eng Pagination: 1054-61 Citation Subset: IM |
Affiliation:
|
Institut Universitaire de Médecine Sociale et Préventive, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Anxiety / ethnology Blood Pressure* Blood Pressure Determination Creatinine / urine European Continental Ancestry Group / ethnology Female Humans Hypertension / ethnology, physiopathology*, psychology Male Middle Aged Periodicity* Potassium / urine Seychelles / ethnology Sodium / urine Switzerland / ethnology |
| Chemical | |
Reg. No./Substance:
|
60-27-5/Creatinine; 7440-09-7/Potassium; 7440-23-5/Sodium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: TERRA: telomeric repeat-containing RNA.
Next Document: The association of microalbuminuria with aortic stiffness is independent of C-reactive protein in es...