Document Detail

Association between serum uric acid and some cardiovascular risk factors in a Chinese population.
MedLine Citation:
PMID:  7937426     Owner:  NLM     Status:  MEDLINE    
The association between serum uric acid concentration and some cardiovascular risk factors was examined in a working Hong Kong Chinese population (mean age 38 years), consisting of 910 men and 603 women. There was no significant age-related rise in serum uric acid concentration. Positive associations were found between serum uric acid concentration and body mass index, waist hip ratio, systolic and diastolic blood pressure, urea, creatinine, protein, glucose (fasting and 2 hours after 75 g oral glucose load), 2 hour insulin, triglycerides, and apolipoprotein B in men. Similar, but fewer, associations were seen in women, with the addition of a positive association with age. In both sexes, serum uric acid was negatively associated with high-density lipoprotein cholesterol. These findings complement the well-known clinical association between gout and cardiovascular and metabolic diseases, such as hypertension, hyperlipidaemia and diabetes mellitus, and suggest that serum uric acid may be a marker for the presence of an adverse cardiovascular risk factor profile.
J Woo; R Swaminathan; C Cockram; E Lau; A Chan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  70     ISSN:  0032-5473     ISO Abbreviation:  Postgrad Med J     Publication Date:  1994 Jul 
Date Detail:
Created Date:  1994-10-26     Completed Date:  1994-10-26     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  486-91     Citation Subset:  IM    
Department of Medicine, Chinese University of Hong Kong.
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MeSH Terms
Aging / blood
Biological Markers / blood
Cardiovascular Diseases / blood*,  ethnology*
Cholesterol, HDL / blood
Hong Kong / epidemiology
Middle Aged
Regression Analysis
Risk Factors
Sex Characteristics
Uric Acid / blood*
Reg. No./Substance:
0/Biological Markers; 0/Cholesterol, HDL; 69-93-2/Uric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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