Document Detail

Association between the serum folate levels and tea consumption during pregnancy.
MedLine Citation:
PMID:  21068474     Owner:  NLM     Status:  In-Process    
Folate is a vital nutrient during pregnancy for the prevention of neural tube defects, intrauterine fetal growth restriction and preeclampsia. Circulating folate levels might be negatively affected by ()-epigallocatechin gallate, which is a tea catechin found in green tea and oolong tea. The aim of this study was to determine whether consumption of green tea or oolong tea was associated with circulating folate levels among pregnant women in Japan. Two hundred and fifty-four healthy women with a singleton pregnancy (age: 30.4 ± 4.7, gestational age: 27.5 ± 9.6 weeks) were recruited from a prenatal clinic in metropolitan Tokyo, Japan. The serum folate levels were measured. Nutrient intake was assessed using a self-administered diet history questionnaire. Information on lifestyle variables was obtained from the questionnaire. The high consumption of green tea or oolong tea was defined as consumption more than 57.3 mL per 1,000 kcal, which is the 75th percentile of participants. The serum folate levels of the participants with high consumption of green tea or oolong tea was significantly lower than those of others (p = 0.027). A multiple regression analysis revealed the high consumption of green tea or oolong tea to be associated with a low serum folate level during pregnancy, after adjusting for confounding variables including dietary folate intake and use of folic acid supplements or multivitamins (β = -0.131, p = 0.016). The association between folate and the consumption of green tea or oolong tea may be useful to clarify the mechanism which links adverse perinatal outcomes and tea consumption.
Mie Shiraishi; Megumi Haruna; Masayo Matsuzaki; Erika Ota; Ryoko Murayama; Sachiyo Murashima
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Bioscience trends     Volume:  4     ISSN:  1881-7823     ISO Abbreviation:  Biosci Trends     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-11-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101502754     Medline TA:  Biosci Trends     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  225-30     Citation Subset:  IM    
Department of Midwifery and Women's Health, Division of Health Sciences and Nursing, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
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