Document Detail


Association between second-trimester cervical length and spontaneous preterm birth in twin pregnancies.
MedLine Citation:
PMID:  21098845     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of this study was to define normal second-trimester cervical length (CL) measurements and to estimate the association between second-trimester CL and spontaneous preterm birth (SPTB) in twin pregnancies.
METHODS: A retrospective cohort of 309 asymptomatic patients with twin pregnancies who had routine outpatient CL assessment in the second trimester was studied. We looked at the gestational age periods of 16 to 17 6/7, 18 to 19 6/7, 20 to 21 6/7, and 22 to 23 6/7 weeks. We estimated the association between the CL measurement during each period and SPTB. A short CL was defined both as a CL at or below the 10th percentile for gestational age and 25 mm or less. We also performed regression analyses controlling for a number of clinically important factors: maternal age, chorionicity, in vitro fertilization, multifetal reduction, prior term births, prior preterm births, prepregnancy body mass index, and cerclage.
RESULTS: The CL measurement at 16 to 17 6/7 weeks was not associated with gestational age at delivery or SPTB. At 18 to 19 6/7 and 20 to 21 6/7 weeks, the CL measurement was not significantly associated with gestational age at delivery or SPTB before 28 and 32 weeks. There was an association with SPTB before 35 weeks. At 22 to 23 6/7 weeks, the CL measurement had a significant association with gestational age at delivery and SPTB before 28, 32, and 35 weeks (P < .05). A short CL at 22 to 23 6/7 weeks was significantly associated with SPTB before 32 and 35 weeks (P < .05).
CONCLUSIONS: In second-trimester twin pregnancies, the strongest association between CL and SPTB is at 22 to 23 6/7 weeks.
Authors:
Nathan S Fox; Andrei Rebarber; Ashley S Roman; Chad K Klauser; Daniel H Saltzman
Related Documents :
1407885 - Effects of digital vaginal examinations on latency period in preterm premature rupture ...
16157125 - Polymorphism of fas and fas ligand in preterm premature rupture of membranes in singlet...
3730345 - The aetiology of preterm labour.
1698335 - Gram stain results from amniocentesis in patients with preterm premature rupture of mem...
18568175 - Cardiac disease in pregnancy.
23429225 - Chorioamnionitis caused by listeria monocytogenes : a case report of ultrasound feature...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  29     ISSN:  1550-9613     ISO Abbreviation:  J Ultrasound Med     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1733-9     Citation Subset:  IM    
Affiliation:
Department of Obstetrics, Gynecology, and Reproductive Science, Mount Sinai School of Medicine, New York, New York, USA. nfox@mfmnyc.com
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Comparison between exclusively long-axis and multiple-axis sonographic protocols for screening of ro...
Next Document:  Model-predicted performance of second-trimester Down syndrome screening with sonographic prenasal th...