| Association between prehypertension and clustering of cardiovascular disease risk factors among Chinese adults. | |
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MedLine Citation:
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PMID: 19454899 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: We aimed to estimate the association between prehypertension (PHT) and clustering of cardiovascular disease (CVD) risk factors among Chinese adults. METHODS: A cross-sectional survey in a nationally representative sample of 15,540 Chinese adults aged 35-74 years was conducted during 2000-2001. RESULTS: Overall, 79.4%, 40.0%, and 11.0% of Chinese adults with PHT (120-139/80-89 mm Hg) had >or=1, >or=2, and >or=3 modifiable CVD risk factors (dyslipidemia, impaired fasting glucose/diabetes, cigarette smoking, and overweight/obesity), respectively. The adjusted odds ratio (95% confidence interval, CI) of having >or=1, >or=2, and >or=3 CVD risk factors was 1.41 (1.24-1.61), 1.45 (1.30-1.61), and 1.96 (1.67-2.29), respectively, for adults with PHT compared with those with optimal blood pressure by multivariate models. Moreover, population attributable risk percent of having >or=1, >or=2, and >or=3 CVD risk factors was 16.7%, 18.0%, and 31.9%, respectively, for adults with PHT. Furthermore, among adults with PHT, higher prevalence, adjusted odds ratios, and population attributable risk percent of having >or=1, >or=2, and >or=3 CVD risk factors were more likely to be found among people with high normal blood pressure (130-139/85-89 mm Hg) compared with their counterparts with normal blood pressure (120-129/80-84 mm Hg). CONCLUSIONS: Clustering of CVD risk factors is common among Chinese adults with PHT, especially with high normal blood pressure. Global lifestyle modification would be a very important nonpharmaceutical therapy to reduce the increasing burden of CVD in China. |
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Authors:
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Dahai Yu; Jianfeng Huang; Dongsheng Hu; Jichun Chen; Jie Cao; Jianxin Li; Dongfeng Gu |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of cardiovascular pharmacology Volume: 53 ISSN: 1533-4023 ISO Abbreviation: J. Cardiovasc. Pharmacol. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-05-20 Completed Date: 2009-08-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7902492 Medline TA: J Cardiovasc Pharmacol Country: United States |
Other Details:
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Languages: eng Pagination: 388-400 Citation Subset: IM |
Affiliation:
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Department of Evidence-Based Medicine, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Age Factors Aged Cardiovascular Diseases / epidemiology*, etiology China / epidemiology Cross-Sectional Studies Diabetes Complications Dyslipidemias / complications Female Humans Hypertension / complications, epidemiology* Male Middle Aged Obesity / complications Population Surveillance Prevalence Risk Assessment Risk Factors Smoking / adverse effects |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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