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Association between pregnancy-induced hypertensive fundus changes and fetal outcomes.
MedLine Citation:
PMID:  21141323     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: Ocular involvement in pregnancy-induced hypertension (PIH) is common.
OBJECTIVE: To study the association between pregnancy-induced hypertensive fundus changes and fetal outcomes.
SUBJECTS AND METHODS: A prospective cohort study was carried out including 153 subjects with the diagnosis of PIH. The subjects were evaluated for hypertensive fundus changes. Fetal outcomes were assessed in terms of gestational age, birth weight, 1 minute Apgar score, stillbirth and neonatal death.
STATISTICS: The chi2 test was used to evaluate the association between the various fundus changes and fetal outcomes using SPSS version 10 software program.
RESULTS: Fundus changes were found in 13.7% of the subjects. The means of systolic and diastolic BP of the subjects with hypertensive fundus changes were 182.86 +/- 33.64 and 125.24 +/- 21.36 respectively, whereas those values without fundus changes were 150.72 +/- 12.86 and 100.07 +/- 9.51.Vitreous hemorrhage, serous retinal detachment and macular star were not found in this study. Fetal outcomes in PIH patients with vascular changes alone were similar to those with no fundus changes. Retinal and optic nerve head changes were found to be associated (p = 0.016) with low birth weight (< 2.5 kg). Choroidal changes and optic nerve head changes were associated with low Apgar score.
CONCLUSION: Retinal and optic nerve head changes are associated with low birth weight. Choroidal changes and optic nerve head changes are associated with low Apgar score. Fundus evaluation in patients with PIH is an important procedure to predict adverse fetal outcomes.
Authors:
P Karki; P Malla; H Das; D K Uprety
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH     Volume:  2     ISSN:  2072-6805     ISO Abbreviation:  Nepal J Ophthalmol     Publication Date:    2010 Jan-Jun
Date Detail:
Created Date:  2010-12-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101505288     Medline TA:  Nepal J Ophthalmol     Country:  Nepal    
Other Details:
Languages:  eng     Pagination:  26-30     Citation Subset:  IM    
Affiliation:
Department of Ophthalmology, KIST Medical College Teaching Hospital, Imadol, Lalitpur, Nepal. poojyashree@hotmail.com
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