Document Detail

Association between maternal panic disorders and pregnancy complications and delivery outcomes.
MedLine Citation:
PMID:  15946784     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The objective of the study was to evaluate the possible association between panic disorders during pregnancy and pregnancy complications, as well as birth outcomes: gestational age and birth weight, as well as preterm birth/low birthweight in newborns. METHODOLOGY: Comparison of newborn infants (without any defects) born to mothers with or without panic disorder in the population-based large data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities. Main outcome measures were medically recorded pregnancy complications, as well as gestational age and birth weight, proportion of preterm birth and low birthweight. PRINCIPAL FINDINGS: Of 38,151 controls, 187 (0.5%) had mothers with panic disorders during pregnancy. Among pregnancy complications, anemia and polyhydramnion showed a higher prevalence in women with panic disorder. There was a higher proportion of males among newborn infants born to mothers with panic diseases compared to newborn infants of mothers without panic disorders. Pregnant women with panic disorders had a shorter (0.4 week) gestational age (adjusted t = 2.3; p = 0.02) and a larger proportion of preterm births (17.1% versus 9.1%) (adjusted POR with 95% CI = 1.9, 1.3-2.8). However, there was no significant difference in the mean birth weight and rate of low birthweight between the two study groups. CONCLUSION: Panic disorders during pregnancy were associated with anemia, a shorter gestational age and a larger proportion of preterm birth. Further studies are needed to confirm and explain or disprove the male excess among newborn infants born to mothers with panic disorders.
Ferenc Bánhidy; Nándor Acs; Erzsébet Puhó; Andrew E Czeizel
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2005-06-08
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  124     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-01-02     Completed Date:  2006-02-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  47-52     Citation Subset:  IM    
Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary.
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MeSH Terms
Anemia / epidemiology,  etiology
Anti-Anxiety Agents / therapeutic use
Birth Weight
Gestational Age
Hungary / epidemiology
Infant, Low Birth Weight
Infant, Newborn
Obstetric Labor, Premature / etiology
Panic Disorder / complications*,  drug therapy
Pregnancy Complications / etiology,  psychology*
Pregnancy Complications, Hematologic / epidemiology
Pregnancy Outcome*
Social Class
Reg. No./Substance:
0/Anti-Anxiety Agents

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