Document Detail


Association between the levels of polyunsaturated fatty acids and blood lipids in healthy individuals.
MedLine Citation:
PMID:  23226783     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The levels of polyunsaturated fatty acids (PUFAs) in blood is closely associated with the status of the health of individuals; in particular, the lack of ω-3 fatty acids may lead to the development of numerous diseases. The aim of this study was to investigate the levels of PUFAs, and their correlation with triglycerides and other factors in blood. The levels of PUFAs and blood lipids were detected in 156 healthy individuals; the blood samples were tested by combined thin-layer and gas liquid chromatographic analysis. The level of ω-3 fatty acids was low in the subjects and the ω-3 index was 4.25%, while the ω-6:ω-3 ratio was at a satisfactory level. There was a strong inverse correlation between ω-3 fatty acids and triglycerides, and a strong positive correlation between ω-3 fatty acids and high density lipoprotein (HDL). Eicosapentaenoic acid and docosahexaenoic acid were inversely correlated with triglycerides, and positively correlated with HDL. In conclusion, ω-3 fatty acids are able to adjust the levels of blood lipids, and lower the levels of triglycerides, which may contribute to human health.
Authors:
Si-Ping Wang; Yan-Hong Chen; Hong Li
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-26
Journal Detail:
Title:  Experimental and therapeutic medicine     Volume:  4     ISSN:  1792-0981     ISO Abbreviation:  Exp Ther Med     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101531947     Medline TA:  Exp Ther Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1107-1111     Citation Subset:  -    
Affiliation:
Department of Special Service of the Chinese PLA General Hospital, Beijing 100853, P.R. China.
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