| Association between hypertension and coronary artery disease as assessed by coronary computed tomography. | |
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MedLine Citation:
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PMID: 21366851 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Multidetector row computed tomography (MDCT) enables the accurate noninvasive assessment of coronary artery stenosis and plaque imaging. The characteristics of patients who have coronary artery disease (CAD) as assessed by MDCT coronary computed tomography (CT) are not well known. Participants consisted of 513 consecutive patients with suspected CAD who underwent coronary CT. The authors quantified patient characteristics, including the prevalence of hypertension (HTN), hyperlipidemia and diabetes mellitus (DM), visceral fat area (VFA) and subcutaneous fat area using CT, and plasma levels of metabolic factors, including adiponectin and leptin. Although plasma levels of adiponectin in men and leptin in women were significantly associated with chronic kidney disease, there were no differences in these levels between patients with and without CAD. HTN was most significantly associated with the presence of CAD by multivariate logistic regression analysis (men, P=.002; women, P=.048). Finally, the percentage of CAD significantly increased as systolic blood pressure increased (trend, P=.0002) in men but not women. In conclusion, hypertension was significantly associated with CAD as assessed by coronary CT. |
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Authors:
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Ryoko Mitsutake; Shin-ichiro Miura; Yuhei Shiga; Yoshinari Uehara; Keijiro Saku |
Publication Detail:
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Type: Journal Article Date: 2011-01-03 |
Journal Detail:
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Title: Journal of clinical hypertension (Greenwich, Conn.) Volume: 13 ISSN: 1751-7176 ISO Abbreviation: J Clin Hypertens (Greenwich) Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-03-03 Completed Date: 2011-06-24 Revised Date: 2012-02-15 |
Medline Journal Info:
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Nlm Unique ID: 100888554 Medline TA: J Clin Hypertens (Greenwich) Country: United States |
Other Details:
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Languages: eng Pagination: 198-204 Citation Subset: IM |
Copyright Information:
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© 2010 Wiley Periodicals, Inc. |
Affiliation:
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Department of Cardiology, Fukuoka University School of Medicine, 7-45-1 Nanakuma, Jonan-ku, Fukuoka, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adiponectin
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blood Aged Body Mass Index Coronary Artery Disease / diagnosis*, epidemiology, pathology Cross-Sectional Studies Female Health Status Indicators Humans Hypertension / blood, diagnosis*, pathology Japan / epidemiology Leptin / blood Logistic Models Male Middle Aged Prevalence Risk Assessment Risk Factors Systole Tomography, X-Ray Computed / instrumentation* |
| Chemical | |
Reg. No./Substance:
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0/Adiponectin; 0/Leptin |
| Comments/Corrections | |
Comment In:
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J Clin Hypertens (Greenwich). 2012 Jan;14(1):67
[PMID:
22235826
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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