| Association between gingival crevicular fluid prostaglandin E 2 level and preterm low birth weight. | |
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MedLine Citation:
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PMID: 22842264 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background: Periodontal infections, which serve as a reservoir of inflammatory mediators such prostaglandin E 2 (PGE 2 ), may pose a threat to the fetal-placental unit and cause preterm delivery. Aim: This study was conducted to estimate the PGE 2 levels in gingival crevicular fluid (GCF) and to explore the association between GCF-PGE 2 levels and preterm low birth weight (PLBW). Materials and Methods: Twenty-two pregnant patients were selected for the study. GCF samples were collected from these patients before delivery and again at 1 month after delivery. PGE 2 level was estimated using a commercially available ELISA kit (Neogen™). Results: The mean GCF-PGE 2 level was 5.8 ng/ml before parturition and 5.5 ng/ml after parturition, but the difference was not statistically significant. There was negative correlation between PGE 2 levels and gestational age at birth. Conclusion: The study provides weak evidence that there is correlation between GCF-PGE 2 levels and birth outcome. Further clinical trials with large samples are required to confirm the association between GCF-PGE 2 levels and PLBW. |
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Authors:
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Fouzia Tarannum; Mohamed Faizuddin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of dental research : official publication of Indian Society for Dental Research Volume: 23 ISSN: 1998-3603 ISO Abbreviation: Indian J Dent Res Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-07-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9202990 Medline TA: Indian J Dent Res Country: India |
Other Details:
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Languages: eng Pagination: 120 Citation Subset: D |
Affiliation:
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Department of Periodontics, MR Ambedkar Dental College and Hospital, Bangalore, Karnataka, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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