Document Detail

Association between daily ambulatory activity patterns and exercise performance in patients with intermittent claudication.
MedLine Citation:
PMID:  18771878     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine the association between daily ambulatory activity patterns and exercise performance in patients with intermittent claudication.
METHODS: One hundred thirty-three patients limited by intermittent claudication participated in this study. Patients were assessed on their ambulatory activity patterns for 1 week with a small, lightweight step activity monitor attached to the ankle using elastic velcro straps above the lateral malleolus of the right leg. The step activity monitor recorded the number of strides taken on a minute-to-minute basis and the time spent ambulating. Patients also were characterized on ankle-brachial index (ABI), ischemic window (IW) after a treadmill test, as well as initial claudication distance (ICD), and absolute claudication distance (ACD) during treadmill exercise.
RESULTS: The patient characteristics (mean +/- SD) were as follows: ABI = 0.71 +/- 0.23, IW = 0.54 +/- 0.72 mm Hg.min.meter(-1), ICD = 236 +/- 198 meters, and ACD = 424 +/- 285 meters. The patients took 3366 +/- 1694 strides/day, and were active for 272 +/- 103 min/day. The cadence for the 30 highest, consecutive minutes of each day (15.1 +/- 7.2 strides/min) was correlated with ICD (r = 0.316, P < .001) and ACD (r = 0.471, P < 0.001), and the cadence for the 60 highest, consecutive minutes of each day (11.1 +/- 5.4 strides/min) was correlated with ICD (r = 0.290, P < .01) and ACD (r = 0.453, P < .001). Similarly, the cadences for the highest 1, 5, and 20 consecutive minutes, and the cadence for the 30 highest, nonconsecutive minutes all were correlated with ICD and ACD (P < .05). None of the ambulatory cadences were correlated with ABI (P > .05) or with ischemic window (P > .05).
CONCLUSION: Daily ambulatory cadences are associated with severity of intermittent claudication, as measured by ACD and ICD, but not with peripheral hemodynamic measures.
Andrew W Gardner; Polly S Montgomery; Kristy J Scott; Steve M Blevins; Azhar Afaq; Raha Nael
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2008-09-04
Journal Detail:
Title:  Journal of vascular surgery     Volume:  48     ISSN:  1097-6809     ISO Abbreviation:  J. Vasc. Surg.     Publication Date:  2008 Nov 
Date Detail:
Created Date:  2008-10-30     Completed Date:  2008-11-13     Revised Date:  2014-09-10    
Medline Journal Info:
Nlm Unique ID:  8407742     Medline TA:  J Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1238-44     Citation Subset:  IM    
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MeSH Terms
Activities of Daily Living*
Ankle / blood supply
Blood Pressure
Brachial Artery / physiopathology
Cross-Sectional Studies
Exercise Test
Exercise Tolerance*
Intermittent Claudication / etiology,  physiopathology*
Ischemia / complications*,  physiopathology
Lower Extremity / blood supply*
Middle Aged
Monitoring, Ambulatory / methods
Severity of Illness Index
Time Factors
Grant Support
M01 RR014467-01A1/RR/NCRR NIH HHS; M01-RR-14467/RR/NCRR NIH HHS; R01 AG016685/AG/NIA NIH HHS; R01 AG016685-01A1/AG/NIA NIH HHS; R01 AG024296/AG/NIA NIH HHS; R01 AG024296-01A2/AG/NIA NIH HHS; R01-AG-16685/AG/NIA NIH HHS; R01-AG-24296/AG/NIA NIH HHS

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