Document Detail

Association between colonization with group B streptococci during pregnancy and preterm delivery among Danish women.
MedLine Citation:
PMID:  11228498     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: We studied the relationship between group B streptococcal colonization and preterm delivery. STUDY DESIGN: In this prospective study at a single hospital in Odense, Denmark, cervicovaginal cultures were obtained at < or = 24 weeks' gestation from all the women, at delivery from women with preterm deliveries, and from a random sample of women delivering at term. RESULTS: In 2846 singleton births, there was no significant association between group B streptococcal colonization at <or = 24 weeks' gestation and preterm birth. After adjustment for the risk factors for preterm delivery, more women with preterm delivery (12/84, 14%) were colonized at delivery with group B streptococci than women with term deliveries (22/300, 7%; adjusted odds ratio, 3.0; 95% confidence interval, 1.4-6.8). Group B streptococcal colonization at < or = 24 weeks' gestation and at delivery was significantly less likely to occur in the presence of normal vaginal flora. CONCLUSION: Group B streptococcal colonization at delivery, but not at < or = 24 weeks' gestation, was associated with preterm delivery.
D R Feikin; P Thorsen; S Zywicki; M Arpi; J G Westergaard; A Schuchat
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  184     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-03-06     Completed Date:  2001-03-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  427-33     Citation Subset:  AIM; IM    
Respiratory Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341-3724, USA.
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MeSH Terms
Anti-Bacterial Agents / therapeutic use*
Case-Control Studies
Cervix Uteri / microbiology
Cohort Studies
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Latex Fixation Tests
Multivariate Analysis
Obstetric Labor, Premature / microbiology*
Pregnancy Complications, Infectious / drug therapy,  microbiology*
Statistics, Nonparametric
Streptococcal Infections / drug therapy,  microbiology*
Streptococcus agalactiae / isolation & purification*
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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