| Association between carotid and coronary artery disease in patients with aortic valve stenosis: an angiographic study. | |
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MedLine Citation:
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PMID: 19049997 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Patients with aortic stenosis have a high prevalence of coronary artery disease, but there is little information about the association of coronary artery disease and carotid artery disease. METHODS: The study includes 317 consecutive patients with aortic stenosis, who underwent carotid and coronary angiography during the same catheterization before aortic valve replacement. RESULTS: At univariate analysis, the prevalence of coronary artery disease was associated with (1) presence of carotid artery disease (P < .001); (2) angina pectoris as presentation symptom (P < .001); (3) age more than 65 years (P < .05); and (4) hypertension (P < .05). At multivariate analysis, only carotid artery disease, angina, and age emerged as independent predictors of coronary artery disease. The combination of 2 variables (carotid artery disease, angina) allowed the identification of 4 groups, with decreasing prevalence of coronary artery disease: (1) angina+/carotid artery disease+: 85%; (2) angina-/ carotid artery disease+: 50%; (3) angina+/carotid artery disease-: 41%; (4) angina-/carotid artery disease-: 21% (P < .001). CONCLUSION: In patients with symptomatic aortic stenosis, the presence of significant carotid artery disease is a strong marker of significant coronary artery disease. |
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Authors:
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Francesco Antonini-Canterin; Elisa Leiballi; Michele Capanna; Claudio Burelli; Matteo Cassin; Franco Macor; Umberto Grandis; Gian Luigi Nicolosi |
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Publication Detail:
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Type: Journal Article Date: 2008-12-01 |
Journal Detail:
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Title: Angiology Volume: 60 ISSN: 1940-1574 ISO Abbreviation: Angiology Publication Date: 2009 Oct-Nov |
Date Detail:
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Created Date: 2009-10-23 Completed Date: 2009-11-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0203706 Medline TA: Angiology Country: United States |
Other Details:
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Languages: eng Pagination: 596-600 Citation Subset: IM |
Affiliation:
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Cardiologia, ARC, Azienda Ospedaliera S. Maria degli Angeli, Pordenone, Italy. cardiologia@aopn.fvg.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Aged Angina Pectoris / etiology Aortic Valve Stenosis / complications, epidemiology, radiography*, surgery Carotid Artery Diseases / complications, epidemiology, radiography* Coronary Angiography* Coronary Artery Disease / complications, epidemiology, radiography* Female Heart Valve Prosthesis Implantation Humans Hypertension / complications Male Middle Aged Multivariate Analysis Predictive Value of Tests Prevalence Prospective Studies Risk Assessment Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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