Document Detail


Association between carotid and coronary artery disease in patients with aortic valve stenosis: an angiographic study.
MedLine Citation:
PMID:  19049997     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Patients with aortic stenosis have a high prevalence of coronary artery disease, but there is little information about the association of coronary artery disease and carotid artery disease. METHODS: The study includes 317 consecutive patients with aortic stenosis, who underwent carotid and coronary angiography during the same catheterization before aortic valve replacement. RESULTS: At univariate analysis, the prevalence of coronary artery disease was associated with (1) presence of carotid artery disease (P < .001); (2) angina pectoris as presentation symptom (P < .001); (3) age more than 65 years (P < .05); and (4) hypertension (P < .05). At multivariate analysis, only carotid artery disease, angina, and age emerged as independent predictors of coronary artery disease. The combination of 2 variables (carotid artery disease, angina) allowed the identification of 4 groups, with decreasing prevalence of coronary artery disease: (1) angina+/carotid artery disease+: 85%; (2) angina-/ carotid artery disease+: 50%; (3) angina+/carotid artery disease-: 41%; (4) angina-/carotid artery disease-: 21% (P < .001). CONCLUSION: In patients with symptomatic aortic stenosis, the presence of significant carotid artery disease is a strong marker of significant coronary artery disease.
Authors:
Francesco Antonini-Canterin; Elisa Leiballi; Michele Capanna; Claudio Burelli; Matteo Cassin; Franco Macor; Umberto Grandis; Gian Luigi Nicolosi
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Publication Detail:
Type:  Journal Article     Date:  2008-12-01
Journal Detail:
Title:  Angiology     Volume:  60     ISSN:  1940-1574     ISO Abbreviation:  Angiology     Publication Date:    2009 Oct-Nov
Date Detail:
Created Date:  2009-10-23     Completed Date:  2009-11-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  596-600     Citation Subset:  IM    
Affiliation:
Cardiologia, ARC, Azienda Ospedaliera S. Maria degli Angeli, Pordenone, Italy. cardiologia@aopn.fvg.it
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Aged
Angina Pectoris / etiology
Aortic Valve Stenosis / complications,  epidemiology,  radiography*,  surgery
Carotid Artery Diseases / complications,  epidemiology,  radiography*
Coronary Angiography*
Coronary Artery Disease / complications,  epidemiology,  radiography*
Female
Heart Valve Prosthesis Implantation
Humans
Hypertension / complications
Male
Middle Aged
Multivariate Analysis
Predictive Value of Tests
Prevalence
Prospective Studies
Risk Assessment
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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