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Association between cardiorespiratory fitness and arterial stiffness in men with the metabolic syndrome.
MedLine Citation:
PMID:  20926153     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
AIMS: We tested the hypothesis that high cardiorespiratory fitness (fitness) is associated with lower levels of arterial stiffness in 1035 (age 52±6 years) men with and without the metabolic syndrome.
METHODS: Arterial stiffness was derived from brachial-ankle pulse wave velocity (baPWV). Fitness was directly measured by peak oxygen uptake during a standard treadmill test.
RESULTS: Men with the metabolic syndrome (n=168) had significantly higher baPWV than men without the metabolic syndrome (1424±175cm/s vs. 1333±150cm/s, p<0.05). When separated according to quartiles of fitness, men with and without the metabolic syndrome in the highest quartile of fitness had significantly lower baPWV compared to men in the lowest quartile of fitness (p<0.05). Fitness was inversely correlated with baPWV in men with (p=-0.29, p<0.05) and without the metabolic syndrome (p=-0.22, p<0.05). There was no differences in baPWV levels between fit men with the metabolic syndrome and unfit men without the metabolic syndrome (fit/MetS; 1366±140 vs. unfit/no MetS; 1401±194cm/s, p=0.81).
CONCLUSIONS: These results demonstrate that high fitness is inversely associated with arterial stiffness in men with and without the metabolic syndrome. Increased arterial stiffness in the metabolic syndrome is attenuated by high fitness.
Authors:
Sae Young Jae; Kevin S Heffernan; Bo Fernhall; Yoo Sung Oh; Won Hah Park; Moon-Kyu Lee; Yoon-Ho Choi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Diabetes research and clinical practice     Volume:  90     ISSN:  1872-8227     ISO Abbreviation:  Diabetes Res. Clin. Pract.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508335     Medline TA:  Diabetes Res Clin Pract     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  326-32     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
The Health and Integrative Physiology Laboratory, Department of Sports Informatics, University of Seoul, Seoul, South Korea.
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