Document Detail


Association between calcium intake and colorectal neoplasia in Puerto Rican Hispanics.
MedLine Citation:
PMID:  21866684     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Epidemiological studies show that a high calcium intake reduces the risk of colon cancer. The objective was to study the association between calcium intake and colorectal neoplasia in a clinic-based sample of Hispanics adults from Puerto Rico. As part of this cross-sectional study, a total of 433 subjects were recruited from surgery and gastroenterology clinics at the University of Puerto Rico. Calcium intake was estimated using a food frequency questionnaire (FFQ) of calcium rich foods. Socio-demographics, health history and colonoscopy results were obtained from the primary study. Chi square and odds ratios (OR) for colorectal neoplasia (adenomas and/ or adenocarcinoma) were calculated for total calcium, dietary calcium and for calcium supplement use. In total, 312 (72%) from 433 participants completed the FFQ and had available colonoscopy results; from these, 196 (62.5%) were free of neoplasia and 117 (37.5%) had colorectal neoplasia. Colorectal neoplasia subjects were older, a lower proportion were females and less educated than those without neoplasia (p < 0.01). Total calcium intake (median 1180 mg/d) was greater in those free of neoplasia compared to colorectal neoplasia subjects (median 1036 mg/d; p<0.05). A high total calcium intake and the use of calcium supplements significantly reduced the OR (crude and age adjusted) for colorectal neoplasia; although these associations lost statistical significance after additionally adjusting for gender and educational level. In conclusion, a high calcium intake and the use of calcium supplements may be protective against colorectal neoplasia, although a greater sample may be required to observe significant associations in a multivariate model.
Authors:
Cristina Palacios; Maritza Lopez; Ana Patricia Ortiz; Marcia Cruz Correa
Related Documents :
1763904 - Self-control and impulsiveness in adult humans when food is the reinforcer.
2324664 - Suboptimal choice in a percentage-reinforcement procedure: effects of signal condition ...
15780464 - The primate amygdala: neuronal representations of the viscosity, fat texture, temperatu...
9952064 - Choice under concurrent vi schedules: comparison of behavior maintained by cocaine or f...
22186014 - Quantification of individual flagellate - bacteria interactions within semi-natural bio...
15969684 - Utility of the ratio of food-specific ige/total ige in predicting symptomatic food alle...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Archivos latinoamericanos de nutrición     Volume:  60     ISSN:  0004-0622     ISO Abbreviation:  Arch Latinoam Nutr     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-08-26     Completed Date:  2011-11-29     Revised Date:  2011-12-19    
Medline Journal Info:
Nlm Unique ID:  0067507     Medline TA:  Arch Latinoam Nutr     Country:  Venezuela    
Other Details:
Languages:  eng     Pagination:  348-54     Citation Subset:  IM    
Affiliation:
University of Puerto Rico, University of North Texas, University of Puerto Rico, San Juan. Puerto Rico.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Aged
Calcium, Dietary / administration & dosage*
Colonoscopy
Colorectal Neoplasms / diagnosis,  epidemiology*,  prevention & control
Cross-Sectional Studies
Diet Records
Dietary Supplements*
Female
Humans
Male
Middle Aged
Puerto Rico / epidemiology
Grant Support
ID/Acronym/Agency:
G12RR-03051/RR/NCRR NIH HHS; K22CA115913/CA/NCI NIH HHS; U50-CCU325128-01-01//PHS HHS
Chemical
Reg. No./Substance:
0/Calcium, Dietary
Comments/Corrections
Erratum In:
Arch Latinoam Nutr. 2011 Mar;61(1):106

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  [Factors associated with overweight in students from tri-border region: Argentina, Brazil and Paragu...
Next Document:  [Salt iodination and excessive iodine intake among schoolchildren].