Document Detail


Association between calcification in the coronary arteries, aortic arch and carotid arteries: the Rotterdam study.
MedLine Citation:
PMID:  16919637     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The present study was performed to examine the prevalence of and associations between calcification in the coronary arteries, aortic arch and carotid arteries, assessed by multislice computed tomography (MSCT), in an elderly population. METHODS AND RESULTS: This study was part of the population-based Rotterdam study. From October 2003 until July 2004, subjects underwent a 16-slice MSCT scan. Calcification was quantified by calculating the Agatston, volume and mass score. Current analyses were performed in 600 subjects (mean age 74 years). The prevalences of calcification in the coronary and carotid arteries were higher in men compared to women. However, aortic arch calcification was more prevalent among women. In men, correlation coefficients based on the Agatston score ranged from 0.40 (between coronary and aortic arch calcification) to 0.54 (between aortic arch and carotid calcification) (p<0.001). Correlation coefficients for women ranged from 0.30 (between coronary and aortic arch calcification) to 0.40 (between coronary and carotid calcification) (p<0.001). CONCLUSIONS: While the prevalences of calcification in the coronary and the carotid arteries were higher in men compared to women, aortic arch calcification was more prevalent among women. Moderate to strong correlations between calcification in different vessel beds were found.
Authors:
Arlette E Odink; Aad van der Lugt; Albert Hofman; Myriam G M Hunink; Monique M B Breteler; Gabriel P Krestin; Jacqueline C M Witteman
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-08-21
Journal Detail:
Title:  Atherosclerosis     Volume:  193     ISSN:  0021-9150     ISO Abbreviation:  Atherosclerosis     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-07-20     Completed Date:  2007-10-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0242543     Medline TA:  Atherosclerosis     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  408-13     Citation Subset:  IM    
Affiliation:
Department of Epidemiology & Biostatistics, Erasmus Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aorta, Thoracic
Aortic Diseases / epidemiology*,  radiography
Calcinosis / epidemiology*,  radiography
Carotid Artery Diseases / epidemiology*,  radiography
Coronary Artery Disease / epidemiology*,  radiography
Female
Humans
Male
Netherlands / epidemiology
Prevalence

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