Document Detail


Association between bronchial asthma in pregnancy and shorter gestational age in a population-based study.
MedLine Citation:
PMID:  16203595     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To study the association between bronchial asthma during pregnancy and gestational age/birth weight, and also preterm birth and low birth weight. METHOD: In the population-based large data set of the Hungarian Case-Control Surveillance System of Congenital Abnormalities, 1980-1996, controls without congenital abnormalities were analysed. RESULTS: Of 38,151 newborn infants, 757 (2.0%) had mothers with bronchial asthma during pregnancy, 88% were medically recorded prospectively. Mothers with bronchial asthma in pregnancy had 0.6 week shorter gestational age and a higher proportion of preterm births (14.1% vs. 9.1%). These findings were reflected with a lower mean birth weight (3,102 vs. 3,279 gram) and higher proportion of low birth weight newborns (9.0% vs. 5.6%). CONCLUSION: The old fashioned anti-asthmatic drugs were not able to prevent the bronchial asthma-related preterm birth, thus there is an urgent need to use modern inhaled therapies.
Authors:
N?ndor Acs; Erzs?bet Puh?; Ferenc B?nhidy; Andrew E Czeizel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  18     ISSN:  1476-7058     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-10-05     Completed Date:  2005-12-23     Revised Date:  2010-03-23    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  107-12     Citation Subset:  IM    
Affiliation:
Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Asthmatic Agents / therapeutic use
Asthma / epidemiology*,  etiology,  prevention & control
Birth Weight
Case-Control Studies
Female
Gestational Age
Humans
Hungary / epidemiology
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Male
Pregnancy
Pregnancy Complications / epidemiology*,  etiology,  prevention & control
Premature Birth
Prospective Studies
Chemical
Reg. No./Substance:
0/Anti-Asthmatic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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