Document Detail


Association between arsenic exposure from drinking water and anemia during pregnancy.
MedLine Citation:
PMID:  16766928     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Arsenic is associated with numerous health effects. We investigated the association between arsenic exposure from drinking water and anemia during pregnancy. METHODS: We conducted a prospective cohort pregnancy study in two Chilean cities with contrasting drinking water arsenic levels: 40 microg/L versus <1 microg/L. This analysis included 810 women who gave birth to live, singleton infants and had at least one hemoglobin determination during pregnancy. RESULTS: Arsenic exposed women were more likely to be anemic during pregnancy after adjusting for other factors. Furthermore, as pregnancy progressed, the prevalence of anemia rose more sharply among those in the exposed versus unexposed city: 49% versus 17%. CONCLUSION: This study suggests an association between moderate arsenic in drinking water and anemia during pregnancy. Further research is needed to identify the specific types of anemia underlying the association.
Authors:
Claudia Hopenhayn; Heather M Bush; Alexander Bingcang; Irva Hertz-Picciotto
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine     Volume:  48     ISSN:  1076-2752     ISO Abbreviation:  J. Occup. Environ. Med.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-06-12     Completed Date:  2006-10-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9504688     Medline TA:  J Occup Environ Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  635-43     Citation Subset:  IM    
Affiliation:
College of Public Health, University of Kentucky, Lexington, Kentucky 40504, USA. cmhope0@uky.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Anemia / epidemiology*
Arsenic / adverse effects*
Chile
Effect Modifiers (Epidemiology)
Environmental Exposure*
Female
Humans
Multivariate Analysis
Pregnancy
Pregnancy Complications, Hematologic / epidemiology*
Prevalence
Prospective Studies
Water Pollutants, Chemical / adverse effects*
Water Supply*
Chemical
Reg. No./Substance:
0/Water Pollutants, Chemical; 7440-38-2/Arsenic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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