| Association between appendicectomy in females and subsequent pregnancy rate: a cohort study. | |
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MedLine Citation:
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PMID: 22683011 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To study whether subsequent pregnancy rate is reduced after appendicectomy. DESIGN: A cohort study was carried out in the General Practice Research Database, a United Kingdom primary care database. SETTING: University hospital. PATIENT(S): Female patients who underwent appendicectomy between 1986 and 2009 and appropriate comparators were followed until first pregnancy. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): The association between appendicectomy and subsequent pregnancy was determined by Cox regression models. RESULT(S): The analyses included 76,426 appendicectomy patients, with 152,852 comparators from the database. There were 30,030 pregnancies (39.3%) in the appendicectomy cohort and 43,321 (28.3%) in the comparator cohort during a mean (SD) follow-up of 10.5 (6.6) years. Adjusted hazard ratios for subsequent birth rates were 1.54 (95% confidence interval, 1.52-1.56). CONCLUSION(S): Appendicectomy was associated with increased subsequent pregnancy rate in this study. This suggests that a history of appendicectomy is not associated with impaired fertility. |
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Authors:
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Li Wei; Thomas Macdonald; Sami Shimi |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-6-7 |
Journal Detail:
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Title: Fertility and sterility Volume: - ISSN: 1556-5653 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-6-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Medicines Monitoring Unit, Division of Medical Sciences, School of Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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