Document Detail


Association between alcohol consumption and postmenopausal breast cancer: results of a case-control study in Montreal, Quebec, Canada.
MedLine Citation:
PMID:  12420948     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To determine the association between postmenopausal breast cancer and prior consumption of alcoholic beverages. METHODS: This case-control study, conducted in all Montreal hospitals between 1996 and 1997, included 556 postmenopausal women (age 50-75 years) who had a new histologically confirmed diagnosis of primary, malignant breast cancer. Control subjects (577) were selected from other histologically confirmed sites of cancer. A detailed history of alcohol consumption and other risk factors was obtained by interview. Indices reflecting alcohol consumption were developed and unconditional logistic regression was used to estimate adjusted odds ratios (OR) and 95% confidence intervals (CI). RESULTS: Current regular drinkers of any type of alcohol were at an increased risk of breast cancer (OR = 1.5; 95% CI 1.0-2.2). For all beverages considered, current regular drinkers showed higher risks than ever regular drinkers. The risk of breast cancer was highest among women who reported exclusive drinking of wine on a weekly or daily basis (e.g. current regular drinking: OR = 2.3; 95% CI 1.2-4.3). Women who started to drink wine on or before the age of 40 were at a 2.5 times increased risk (95% CI 1.4-4.4). CONCLUSIONS: Our findings provide further support for a positive association between the risk of postmenopausal breast cancer and alcohol consumption.
Authors:
Sarah K Lenz; Mark S Goldberg; France Labrèche; Marie-Elise Parent; Marie-France Valois
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cancer causes & control : CCC     Volume:  13     ISSN:  0957-5243     ISO Abbreviation:  Cancer Causes Control     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-11-07     Completed Date:  2003-02-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9100846     Medline TA:  Cancer Causes Control     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  701-10     Citation Subset:  IM    
Affiliation:
Canadian Institute for Health Information, Toronto, Ontario.
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MeSH Terms
Descriptor/Qualifier:
Aged
Alcohol Drinking / adverse effects*
Breast Neoplasms / etiology*
Case-Control Studies
Female
Humans
Logistic Models
Middle Aged
Odds Ratio
Postmenopause*
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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