Document Detail

Association between acute pancreatitis and peptic ulcer disease.
MedLine Citation:
PMID:  21448359     Owner:  NLM     Status:  MEDLINE    
AIM: To evaluate the relationship between peptic ulcer disease (PUD) and acute pancreatitis.
METHODS: A cohort of 78 patients with acute pancreatitis were included in this study. The presence of PUD and the Helicobacter pylori (H. pylori) status were assessed by an endoscopic method. The severity of acute pancreatitis was assessed using Ranson's score, the Acute Physiology and Chronic Health Evaluation (APACHE) II score, computed tomography severity index and the clinical data during hospitalization, all of which were compared between the patients with and without PUD. The risk factors for PUD were also evaluated.
RESULTS: Among 78 patients, 41 patients (52.6%) with acute pancreatitis suffered from PUD, but only 13 (31.7%) patients with PUD were infected by H. pylori. On univariate analysis, male gender, an etiology of alcohol-induced pancreatitis, a history of smoking or alcohol consumption, elevated triglyceride and C-reactive protein levels, and high APACHE II score were significantly associated with PUD. However, on multivariate logistic regression analysis, the APACHE II score (odds ratio: 7.69; 95% confidence interval: 1.78-33.33; P < 0.01) was found to be the only independent risk factor for PUD.
CONCLUSION: Patients with acute pancreatitis are liable to suffer from PUD. PUD is associated with severe acute pancreatitis according to the APACHE II score, and treatment for PUD should be considered for patients with severe acute pancreatitis.
Kang-Moon Lee; Chang-Nyol Paik; Woo Chul Chung; Jin Mo Yang
Related Documents :
20404719 - A novel bioimpedance technique to monitor fluid volume state during hemodialysis treatm...
7130829 - Serum erythropoietin (esf) titers in anemia of chronic renal failure.
17371779 - National survey of heparin-induced thrombocytopenia in the haemodialysis population of ...
18344239 - Evolution of large-vessel arteriopathy in paediatric patients with chronic kidney disease.
19789539 - Licorice: a sweet alternative to prevent hyperkalemia in dialysis patients?
19875379 - The effect of dialysis modality on phosphate control : haemodialysis compared to haemod...
2025169 - Optic nerve sheath decompression for nonarteritic ischemic optic neuropathy improves mu...
23996289 - Soluble e-cadherin in systemic lupus erythematosus.
15014899 - Aneurysmatic dilatation of ascending aorta in a patient with beta-thalassemia and a pse...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  17     ISSN:  2219-2840     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-03-30     Completed Date:  2011-07-18     Revised Date:  2014-05-20    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  1058-62     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Helicobacter Infections / complications
Middle Aged
Pancreatitis / complications*
Peptic Ulcer / etiology*,  microbiology
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Detection of early gastric cancer using hydro-stomach CT: blinded vs unblinded analysis.
Next Document:  Antioxidative status of patients with alcoholic liver disease in southeastern Taiwan.