| Association between TaqIB polymorphism of cholesteryl ester transfer protein and coronary artery disease in the Chinese population. | |
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MedLine Citation:
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PMID: 22556171 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess whether the TaqIB polymorphism of cholesteryl ester transfer protein (CETP) is associated with coronary artery disease (CAD) in Chinese population, we performed a meta-analysis in this paper. METHODS: We searched PubMed, Embase, the Science Citation Index (SCI), the China Biological Medicine database (CBM), the China National Knowledge Infrastructure (CNKI), and the Wanfang database for relevant articles. Data were extracted, and pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. RESULTS: The literature search yielded 448 studies, in which 10 case-control studies including 1694 cases and 1456 controls matched the selection criteria. The combined B1 and B2 allele frequencies were 0.587 and 0.413, respectively. The pooled OR was 1.10 (95% CI, 0.89-1.34) for comparing the B1B1 or B1B2 carriers with B2B2 carriers, and was 1.27 (95% CI, 1.09-1.49) in the B1B1 carriers versus B2B2 or B1B2 carriers. CONCLUSIONS: In the present study, the TaqIB polymorphism of CETP was found to be associated with CAD in the Chinese population. |
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Authors:
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Qi Yu; En-qi Liu; Si-hai Zhao; Ya-feng Li; Yan-li Wang; Yu-long Chen; Ke-na Wei; Bing-qiao Huang; Jian-lin Fan; Peng-hui Yang |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of Zhejiang University. Science. B Volume: 13 ISSN: 1862-1783 ISO Abbreviation: J Zhejiang Univ Sci B Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-05-04 Completed Date: 2012-09-10 Revised Date: 2013-03-01 |
Medline Journal Info:
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Nlm Unique ID: 101236535 Medline TA: J Zhejiang Univ Sci B Country: China |
Other Details:
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Languages: eng Pagination: 342-7 Citation Subset: IM |
Affiliation:
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Research Institute of Atherosclerotic Disease, Xi'an Jiaotong University School of Medicine, Shaanxi, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over China / epidemiology Cholesterol Ester Transfer Proteins / genetics* Coronary Artery Disease / epidemiology*, genetics* Female Genetic Association Studies Genetic Predisposition to Disease / epidemiology*, genetics* Heterozygote* Humans Male Middle Aged Polymorphism, Single Nucleotide / genetics* Prevalence Risk Assessment Risk Factors Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol Ester Transfer Proteins |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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