| Association between Takayasu arteritis and ulcerative colitis - case report and review of serological HLA analysis. | |
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MedLine Citation:
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PMID: 21709638 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background: Takayasu arteritis and ulcerative colitis are immune-mediated inflammatory diseases; genetic factors are assumed to play an important role in the pathogenesis of these 2 diseases. However, the coexistence of these 2 diseases has rarely been reported.<br /> Case Report: In this report, we present a rare case of a 29-year-old man with a 4 years history of ulcerative colitis who developed Takayasu arteritis. He was found to carry the following human leukocyte antigens (HLA): A11, A24, B52, B62, DR4, and DR9.<br /> Conclusions: We present a case report and review of the pertinent literature on serological analysis of HLA haplotype of the patients who exhibit both these diseases. In patients with both Takayasu arteritis and ulcerative colitis, high frequency of HLA-A24, B52, and DR 2 is observed. The pathological relevance of HLA-A24, B52, and DR2 to concomitant Takayasu arteritis and ulcerative colitis requires further investigation.<br /> |
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Authors:
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Nobuyuki Takahashi; Kazuaki Tanabe; Takashi Sugamori; Masatake Sato; Jun Kitamura; Hidetoshi Sato; Hiroyuki Yoshitomi; Yutaka Ishibashi; Toshio Shimada |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Medical science monitor : international medical journal of experimental and clinical research Volume: 17 ISSN: 1643-3750 ISO Abbreviation: Med. Sci. Monit. Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2011-06-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9609063 Medline TA: Med Sci Monit Country: Poland |
Other Details:
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Languages: eng Pagination: CS81-84 Citation Subset: IM |
Affiliation:
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4th Department of Internal Medicine, Shimane University Faculty of Medicine, Izumo City, Shimane, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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