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Association between Salt Intake and Albuminuria in Normotensive and Hypertensive Individuals.
MedLine Citation:
PMID:  24171109     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Background. There is a little published data regarding the association between salt intake and albuminuria as an important alarm for progression of cardiovascular and renal dysfunction. We aimed to assess this relationship to emphasize the major role of restricting salt intake to minimize albuminuria and prevent these life-threatening events. Methods. The study population comprised 820 individuals. Participants were assigned to groups as follows: normal albuminuria, slight albuminuria, and clinical albuminuria. Daily salt intake was assessed on the basis of 24-hour urinary sodium excretion, since urinary sodium excretion largely equals sodium intake. Results. In normotensive participants, the mean level of urine albumin was higher in those who had higher amounts of salt intake with a significantly upward trend (the mean urinary albumin level in low-salt-diet group, in medium-salt-intake group, and in high-salt-intake group was 42.70 ± 36.42, 46.89 ± 38.91, and 53.38 ± 48.23, resp., (P = 0.017)). There was a significant positive correlation between 24-hour urinary sodium secretion and the level of urine albumin (beta = 0.130, P < 0.001). The amount of salt intake was significantly associated with urine albumin concentration (beta = 3.969, SE = 1.671, P = 0.018). Conclusion. High salt intake was shown to be associated with higher level of microalbuminuria even adjusted for potential underlying risk factors.
Authors:
Arsalan Khaledifar; Mojagn Gharipour; Ahmad Bahonar; Nizal Sarrafzadegan; Alireza Khosravi
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Publication Detail:
Type:  Journal Article     Date:  2013-09-19
Journal Detail:
Title:  International journal of hypertension     Volume:  2013     ISSN:  2090-0384     ISO Abbreviation:  Int J Hypertens     Publication Date:  2013  
Date Detail:
Created Date:  2013-10-30     Completed Date:  2013-10-30     Revised Date:  2013-11-04    
Medline Journal Info:
Nlm Unique ID:  101538881     Medline TA:  Int J Hypertens     Country:  United States    
Other Details:
Languages:  eng     Pagination:  523682     Citation Subset:  -    
Affiliation:
Cardiology Department, School of medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.
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