| Association between the Ratio of Triglycerides to High-Density Lipoprotein Cholesterol and Chronic Kidney Disease in Korean Adults: The 2005 Korean National Health and Nutrition Examination Survey. | |
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MedLine Citation:
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PMID: 21502765 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: The ratio of triglycerides (TG, mg/dl) to high-density lipoprotein cholesterol (HDL-C, mg/dl) is a reliable indicator of insulin resistance and atherosclerotic diseases. The purpose of this study was to examine the association between TG/HDL-C and chronic kidney disease (CKD) in a nationally representative sample of Korean adults. Methods: This cross-sectional study included 5,503 subjects (≥19 years of age) who participated in the 2005 Korean National Health and Nutrition Examination Survey. CKD was defined as an estimated glomerular filtration rate (eGFR) below 60 ml/min/1.73 m(2) as calculated by the abbreviated formula from the Modification of Diet in Renal Disease study. Results: The overall prevalence of CKD in our sample was 9.0%. eGFR was negatively correlated with logarithm-transformed TG/HDL-C in Pearson's correlation. The prevalence of CKD in increasing TG/HDL-C quintiles was 4.4, 6.6, 9.5, 11.9, and 12.8%. In comparison with the lowest quintile of TG/HDL-C (<1.38), the odds ratio (95% confidence interval) for CKD in the highest quintile of TG/HDL-C (≥4.50) was 2.15 (1.38-3.37), after adjustment for multiple covariates (p value for trend = 0.036). Conclusions: TG/HDL-C was independently associated with increased prevalence of CKD in a sample of Korean adults. |
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Authors:
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Hee-Taik Kang; Jae-Yong Shim; Yong-Jae Lee; Jung-Eun Lee; John A Linton; Jong-Koo Kim; Hye-Ree Lee |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-18 |
Journal Detail:
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Title: Kidney & blood pressure research Volume: 34 ISSN: 1423-0143 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610505 Medline TA: Kidney Blood Press Res Country: - |
Other Details:
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Languages: ENG Pagination: 173-179 Citation Subset: - |
Copyright Information:
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Copyright © 2011 S. Karger AG, Basel. |
Affiliation:
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Department of Family Medicine, Wonju College of Medicine, Yonsei University, Wonju, South Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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