Document Detail


Association between physical activity and retinal microvascular signs: the Atherosclerosis Risk in Communities (ARIC) Study.
MedLine Citation:
PMID:  20618695     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To examine the association between physical activity measured during leisure, sport, and work and retinal microvascular signs.
METHODS: Participants of the Atherosclerosis Risk in Communities (ARIC) Study, a population-based cross-sectional study, had retinal photographs taken at their third follow up visit (1993-1995). Retinal microvascular signs were assessed using a standardized protocol and retinal vascular caliber by a computer-assisted method. Leisure, sport, and work-related physical activity levels were determined through a modified Baecke physical activity questionnaire.
RESULTS: A higher level of physical activity during sport and work was significantly associated with a lower prevalence of arteriovenous (AV) nicking, wider venular caliber, and retinopathy. In multivariate models, persons with a level of sport-related physical activity above the median were less likely to have AV nicking (odds ratio [OR] = 0.87; 95% confidence interval [CI] 0.78-0.97) and wider retinal venules (OR = 0.91; 95% CI: 0.83-0.99). Persons with a level of work-related physical activity above the median were less likely to have diabetic retinopathy (OR = 0.66, 95% CI: 0.51-0.85).
CONCLUSIONS: In this cross-sectional analyzes, higher levels of physical activity was associated with a lower prevalence of retinal microvascular abnormalities.
Authors:
Gabriella Tikellis; Satyamurthy Anuradha; Ronald Klein; Tien Yin Wong
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Microcirculation (New York, N.Y. : 1994)     Volume:  17     ISSN:  1549-8719     ISO Abbreviation:  Microcirculation     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-10-29     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  9434935     Medline TA:  Microcirculation     Country:  United States    
Other Details:
Languages:  eng     Pagination:  381-93     Citation Subset:  IM    
Affiliation:
Murdoch Children's Research Institute, Parkville, Victoria, Australia.
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MeSH Terms
Descriptor/Qualifier:
Aged
Analysis of Variance
Atherosclerosis / etiology*
Cross-Sectional Studies
Diabetic Retinopathy / epidemiology,  etiology*
Female
Fluorescein Angiography
Humans
Leisure Activities
Male
Middle Aged
Motor Activity / physiology*
Questionnaires
Retinal Vessels / pathology*
Risk Factors
Sports
United States / epidemiology
Work
Grant Support
ID/Acronym/Agency:
N01-HC-35125/HC/NHLBI NIH HHS; N01-HC-35126/HC/NHLBI NIH HHS; N01-HC-55015/HC/NHLBI NIH HHS; N01-HC-55016/HC/NHLBI NIH HHS; N01-HC-55018/HC/NHLBI NIH HHS; N01-HC-55019/HC/NHLBI NIH HHS; N01-HC-55020/HC/NHLBI NIH HHS; N01-HC-55021/HC/NHLBI NIH HHS; N01-HC-55022/HC/NHLBI NIH HHS; R01 HL069979-02/HL/NHLBI NIH HHS; R01 HL069979-02S1/HL/NHLBI NIH HHS; R01 HL069979-03/HL/NHLBI NIH HHS; R01 HL069979-04/HL/NHLBI NIH HHS; R21 HL077166-02/HL/NHLBI NIH HHS
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