Document Detail


Association of the adiponectin rs266729 C>G variant and coronary heart disease in the low risk 'Golden Years' type 1 diabetes cohort.
MedLine Citation:
PMID:  21208676     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The C-allele of rs266729 is associated with CHD, while the G-allele of rs17300539 is associated with metabolic traits. We examined these in type 1 diabetes. For rs266729, the C-allele was associated with 8-fold increase in CHD. For rs17300539, the G-allele was associated with increases in triglycerides and waist circumference.
Authors:
Sarah L Prior; Danielle A Jones; Geoffrey V Gill; Steve C Bain; Jeffrey W Stephens
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-01-03
Journal Detail:
Title:  Diabetes research and clinical practice     Volume:  91     ISSN:  1872-8227     ISO Abbreviation:  Diabetes Res. Clin. Pract.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-11     Completed Date:  2011-08-08     Revised Date:  2012-04-09    
Medline Journal Info:
Nlm Unique ID:  8508335     Medline TA:  Diabetes Res Clin Pract     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  e71-4     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Diabetes Research Group, Institute of Life Science, Swansea University, Swansea SA2 8PP, UK. s.l.prior@swansea.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Adiponectin / genetics
Aged
Coronary Disease / complications,  genetics*
Diabetes Mellitus, Type 1 / complications,  genetics*
Humans
Middle Aged
Point Mutation
Polymorphism, Single Nucleotide*
Triglycerides / blood
Waist Circumference / genetics
Chemical
Reg. No./Substance:
0/ADIPOQ protein, human; 0/Adiponectin; 0/Triglycerides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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