Document Detail

Association of L-tryptophan and an illness resembling eosinophilic fasciitis. Clinical and histopathologic findings in four patients with eosinophilia-myalgia syndrome.
MedLine Citation:
PMID:  2369428     Owner:  NLM     Status:  MEDLINE    
The Centers for Disease Control has recently reported an association between the use of oral L-tryptophan preparations and a disease marked by severe myalgia, peripheral eosinophilia, and neuromuscular and cutaneous abnormalities. They have labeled the condition eosinophilia-myalgia syndrome. We report here the clinical and histopathologic findings in 4 patients who developed an illness resembling eosinophilic fasciitis following the initiation of oral L-tryptophan supplementation.
K J Bulpitt; M A Verity; P J Clements; H E Paulus
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Arthritis and rheumatism     Volume:  33     ISSN:  0004-3591     ISO Abbreviation:  Arthritis Rheum.     Publication Date:  1990 Jul 
Date Detail:
Created Date:  1990-08-13     Completed Date:  1990-08-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370605     Medline TA:  Arthritis Rheum     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  918-29     Citation Subset:  AIM; IM    
Department of Medicine, University of California, Los Angeles School of Medicine.
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MeSH Terms
Eosinophilia / chemically induced*,  pathology
Fasciitis / chemically induced*,  pathology
Muscular Diseases / chemically induced,  pathology
Skin / pathology
Tryptophan / adverse effects*
Reg. No./Substance:

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