| Association of Inflammatory Biomarkers with Metabolic Syndrome in Hemodialysis Patients. | |
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MedLine Citation:
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PMID: 22889096 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The relative importance of inflammatory markers in relation with metabolic syndrome (MeS) in hemodialysis (HD) patients is uncertain. This study investigated the association between MeS and high-sensitive C-reactive protein (hsCRP), hallmark of inflammation, and other inflammatory-related biomarkers. The study included 153 patients who were dialyzed at least for the last 3 months. The serum level of hsCRP was assessed by high-sensitive Enzyme-linked immunosorbent assay (ELISA). MeS was defined using the modified National Cholesterol Education Program Adult Treatment Panel III (ATP-III). Ninety-one HD patients (59.5%) were diagnosed as having MeS. Lower level of high-density lipoprotein-cholesterol (HDL-C) was the most prevalent MeS component (85.6%). The serum level of hsCRP in these patients was significantly higher than that in HD patients without MeS (2.3 ± 1.7 vs. 1.7 ± 1.6 mg/dL, p = 0.03). A significant linear increase in the hsCRP levels was found according to the number of MeS components (β = 0.09, p = 0.022). The study concluded that increasing inflammatory biomarkers, especially hsCRP, is associated with MeS in HD patients. |
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Authors:
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Shabnam Shahrokh; Peimaneh Heydarian; Farokhlagha Ahmadi; Fereshteh Saddadi; Effat Razeghi |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-14 |
Journal Detail:
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Title: Renal failure Volume: - ISSN: 1525-6049 ISO Abbreviation: Ren Fail Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8701128 Medline TA: Ren Fail Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Nephrology Research Center, Tehran University of Medical Sciences , Tehran , Iran. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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