| Association of diabetes and hemodialysis with ankle pressure and ankle-brachial index in Japanese patients with critical limb ischemia. | |
| | |
MedLine Citation:
|
PMID: 22723344 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To investigate whether diabetes and regular hemodialysis are associated with false elevation of ankle systolic blood pressure and ankle-brachial systolic pressure index (ABI) because of their arterial calcification in patients with critical limb ischemia (CLI). RESEARCH DESIGN AND METHODS: We recruited 269 Japanese patients who underwent endovascular therapy for CLI. Ankle systolic blood pressure and ABI were assessed before endovascular therapy. Arterial stenosis and calcification were evaluated angiographically. We investigated the associations among clinical comorbidities, arterial calcification, and measurements of ankle systolic blood pressure and ABI. RESULTS: Ankle systolic blood pressure was 85 ± 56 mmHg, and ABI was 0.59 ± 0.37. Arterial calcification was observed in 69% of the patients. The prevalence of diabetes and regular hemodialysis was 71 and 47%. Diabetes and regular hemodialysis were both significantly associated with the presence of arterial calcification; their adjusted odds ratios were 2.33 (P = 0.01) and 7.40 (P < 0.01), respectively. However, there was no significant difference in ankle systolic blood pressure or ABI level between those with and without these comorbidities. Furthermore, the presence of arterial calcification was not associated with ankle systolic blood pressure or ABI level, whereas arterial stenoses of all segments in the lower body had independent associations with reduced ankle systolic blood pressure and ABI level. CONCLUSIONS: Diabetes and regular hemodialysis were significantly associated with arterial calcification, but not with elevated measurements of ankle systolic blood pressure or ABI, in CLI patients. |
| | |
Authors:
|
Mitsuyoshi Takahara; Hideaki Kaneto; Osamu Iida; Naoto Katakami; Taka-Aki Matsuoka; Masahiko Ikeda; Iichiro Shimomura |
Related Documents
:
|
11811364 - Muscle sympathetic nerve activity in blood pressure control against gravitational stress. 2459674 - The usefulness of head-up tilt testing and hemodynamic investigations in the workup of ... 20651224 - Delayed vasoconstrictor response to venous pooling in the calf is associated with high ... 3608254 - The hemodynamic and humoral responses to tilting in diabetic patients on chronic hemodi... 22432524 - Measurement of vapor pressures and heats of sublimation of dicarboxylic acids using atm... 21142454 - Prevention of facial pressure ulcers using the mayfield clamp for sacral tumor resection. |
Publication Detail:
|
Type: Journal Article Date: 2012-06-20 |
Journal Detail:
|
Title: Diabetes care Volume: 35 ISSN: 1935-5548 ISO Abbreviation: Diabetes Care Publication Date: 2012 Oct |
Date Detail:
|
Created Date: 2012-09-21 Completed Date: 2013-02-20 Revised Date: 2013-04-16 |
Medline Journal Info:
|
Nlm Unique ID: 7805975 Medline TA: Diabetes Care Country: United States |
Other Details:
|
Languages: eng Pagination: 2000-4 Citation Subset: IM |
Affiliation:
|
Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Ankle / blood supply Ankle Brachial Index* Asian Continental Ancestry Group Blood Pressure* Brachial Artery / physiology Calcinosis / etiology Diabetes Mellitus / physiopathology* Female Humans Ischemia / complications, physiopathology* Leg / blood supply Male Middle Aged Peripheral Arterial Disease / complications, diagnosis Renal Dialysis / adverse effects |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Modest levels of physical activity are associated with a lower incidence of diabetes in a population...
Next Document: Structure and backbone dynamics of a microcrystalline metalloprotein by solid-state NMR.