| Association of depression with antihypertensive medication adherence in older adults: cross-sectional and longitudinal findings from CoSMO. | |
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MedLine Citation:
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PMID: 20703839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Little is known about the associations between depressive symptoms, social support and antihypertensive medication adherence in older adults. PURPOSE: We evaluated the cross-sectional and longitudinal associations between depressive symptoms, social support and antihypertensive medication adherence in a large cohort of older adults. METHODS: A cohort of 2,180 older adults with hypertension was administered questionnaires, which included the Center for Epidemiologic Studies-Depression Scale, the Medical Outcomes Study Social Support Index, and the hypertension-specific Morisky Medication Adherence Scale at baseline and 1 year later. RESULTS: Overall, 14.1% of participants had low medication adherence, 13.0% had depressive symptoms, and 33.9% had low social support. After multivariable adjustment, the odds ratios that participants with depressive symptoms and low social support would have low medication adherence were 1.96 (95% confidence interval (CI) 1.43, 2.70) and 1.27 (95% CI 0.98, 1.65), respectively, at baseline and 1.87 (95% CI 1.32, 2.66) and 1.30 (95% CI 0.98, 1.72), respectively, at 1 year follow-up. CONCLUSION: Depressive symptoms may be an important modifiable barrier to antihypertensive medication adherence in older adults. |
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Authors:
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Marie Krousel-Wood; Tareq Islam; Paul Muntner; Elizabeth Holt; Cara Joyce; Donald E Morisky; Larry S Webber; Edward D Frohlich |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Annals of behavioral medicine : a publication of the Society of Behavioral Medicine Volume: 40 ISSN: 1532-4796 ISO Abbreviation: Ann Behav Med Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-08 Completed Date: 2011-02-18 Revised Date: 2011-09-26 |
Medline Journal Info:
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Nlm Unique ID: 8510246 Medline TA: Ann Behav Med Country: United States |
Other Details:
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Languages: eng Pagination: 248-57 Citation Subset: IM |
Affiliation:
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Center for Health Research, Ochsner Clinic Foundation, 1514 Jefferson Highway, New Orleans, LA 70121, USA. mawood@ochsner.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Antihypertensive Agents / adverse effects* Cross-Sectional Studies Depression / etiology* Female Humans Hypertension / drug therapy* Longitudinal Studies Male Medication Adherence* Questionnaires Social Support* |
| Grant Support | |
ID/Acronym/Agency:
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R01 AG022536/AG/NIA NIH HHS; R01 AG022536-04/AG/NIA NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents |
| Comments/Corrections | |
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