Document Detail


Association of Coronary Artery Calcium With Severity of Myocardial Ischemia in Left Anterior Descending, Left Circumflex, and Right Coronary Artery Territories.
MedLine Citation:
PMID:  22083587     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: An increasing coronary artery calcium score is associated with a higher likelihood of myocardial ischemia. HYPOTHESIS: The association of the coronary calcium score with myocardial ischemia in different coronary arteries needed to be investigated. METHODS: We correlated the coronary artery calcium (CAC) score with the severity of myocardial ischemia diagnosed by myocardial perfusion imaging in the left anterior descending (LAD), left circumflex (LCX), and right coronary artery (RCA) territories in 206 patients, mean age 66 years, without cardiac stents or coronary artery surgery. RESULTS: The mean CAC score in the LAD coronary artery was 160 ± 218 in patients with no or mild ischemia and 336 ± 379 in patients with moderate or severe ischemia (P = 0.039). The mean CAC score in the LCX coronary artery was 57 ± 117 in patients with no or mild ischemia and 161 ± 191 in patients with moderate or severe ischemia (P = 0.018). The mean CAC score in the RCA was 114 ± 237 in patients with no or mild ischemia and 261 ± 321 in patients with moderate or severe ischemia (P = 0.045). Stepwise linear regression analysis showed that male gender (P < 0.0001), age (P < 0.0001), and moderate or severe ischemia (P = 0.023) were significantly associated with high LAD coronary artery CAC scores. Male gender (P < 0.0001), age (P = 0.0002), and moderate or severe ischemia (P = 0.006) were significantly associated with high LCX coronary artery CAC scores. Male gender (P < 0.0001) and age (P < 0.0001) were significantly associated with high RCA CAC scores. CONCLUSIONS: Higher CAC scores are significantly associated with moderate or severe ischemia in the LAD and LCX coronary arteries. © 2011 Wiley Periodicals, Inc. The authors have no funding, financial relationships, or conflicts of interest to disclose.
Authors:
Hoang M Lai; Dvorah Holtzman; Wilbert S Aronow; Albert J Deluca; Chul Ahn; Svetlana Matayev; Robert N Belkin
Related Documents :
15642527 - Colour m-mode velocity propagation: a glance at intra-ventricular pressure gradients an...
19121567 - Feasibility of prediction of myocardial viability with doppler tissue imaging following...
19821817 - Segmental differences of impaired diastolic relaxation following cardiopulmonary bypass...
7963107 - Abnormal coronary flow dynamics at rest and during tachycardia associated with impaired...
7612317 - Assessment of the practicality and safety of thrombolysis with anistreplase given by ge...
23917507 - Myocardial infarction area quantification using high-resolution spect images in rats.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-14
Journal Detail:
Title:  Clinical cardiology     Volume:  -     ISSN:  1932-8737     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 Wiley Periodicals, Inc.
Affiliation:
Cardiology Division, Department of Medicine, New York Medical College, Valhalla, New York. hoanglai@hotmail.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Small Molecule Immunomodulatory Drugs: Challenges and Approaches for Balancing Efficacy with Toxicit...
Next Document:  HDXFinder: automated analysis and data reporting of deuterium/hydrogen exchange mass spectrometry.