Document Detail

The association between lower extremity continuous peripheral nerve blocks and patient falls after knee and hip arthroplasty.
MedLine Citation:
PMID:  20889937     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Continuous peripheral nerve blocks (CPNB) may induce muscle weakness, and multiple recently published series emphasize patient falls after postarthroplasty CPNB. However, none have included an adequate control group, and therefore the relationship between CPNB and falls remains speculative.
METHODS: We pooled data from 3 previously published, randomized, triple-masked, placebo-controlled studies of CPNB involving the femoral nerve after knee and hip arthroplasty.
RESULTS: No patients receiving perineural saline (n = 86) fell (0%; 95% confidence interval [CI] = 0%-5%), but there were 7 falls in 6 patients receiving perineural ropivacaine (n = 85; 7%; 95% CI = 3%-15%; Fisher's exact test P = 0.013).
CONCLUSIONS: Our analysis suggests that there is a causal relationship between CPNB and the risk of falling after knee and hip arthroplasty.
Brian M Ilfeld; Kimberly B Duke; Michael C Donohue
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2010-10-01
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  111     ISSN:  1526-7598     ISO Abbreviation:  Anesth. Analg.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-25     Completed Date:  2011-01-07     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1552-4     Citation Subset:  AIM; IM    
Department of Anesthesiology, University of California San Diego, San Diego, California, USA.
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MeSH Terms
Accidental Falls*
Arthroplasty, Replacement, Hip / adverse effects*
Arthroplasty, Replacement, Knee / adverse effects*
Chi-Square Distribution
Lower Extremity
Middle Aged
Multicenter Studies as Topic
Muscle Weakness / etiology
Muscle, Skeletal / innervation*
Nerve Block / adverse effects*
Randomized Controlled Trials as Topic
Risk Assessment
Risk Factors
Treatment Outcome
Grant Support
Comment In:
Anesth Analg. 2011 Aug;113(2):428-9; author reply 429-30   [PMID:  21788330 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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