| Association of Bartonella species and Coxiella burnetii infection with coronary artery disease. | |
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MedLine Citation:
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PMID: 11181164 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Coronary artery disease is an inflammatory condition associated with several infections. We prospectively evaluated 155 consecutive patients undergoing coronary angiography for evidence of Bartonella species and Coxiella burnetii infection. All Bartonella cultures were found to be negative. Multivariable logistic regression analysis that controlled for potential confounding factors revealed no association between coronary artery disease and seropositivity to Bartonella henselae (odds ratio [OR], 0.852; 95% confidence interval [CI], 0.293-2.476), Bartonella quintana (OR, 0.425; 95% CI, 0.127-1.479), C. burnetii phase 1 (OR, undefined), and C. burnetii phase 2 (OR, 0.731; 95% CI, 0.199-2.680). The geometric mean titer (GMT) for C. burnetii phase 1 assay was slightly higher in persons with coronary artery disease than in those without such disease (P<.02). B. henselae, B. quintana, and C. burnetii seropositivity was not strongly associated with coronary artery disease. On the basis of GMTs, C. burnetii infection may have a modest association with coronary artery disease. |
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Authors:
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P T Ender; J Phares; G Gerson; S E Taylor; R Regnery; R C Challener; M J Dolan |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. Date: 2001-01-24 |
Journal Detail:
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Title: The Journal of infectious diseases Volume: 183 ISSN: 0022-1899 ISO Abbreviation: J. Infect. Dis. Publication Date: 2001 Mar |
Date Detail:
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Created Date: 2001-02-22 Completed Date: 2001-03-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0413675 Medline TA: J Infect Dis Country: United States |
Other Details:
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Languages: eng Pagination: 831-4 Citation Subset: AIM; IM |
Affiliation:
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Division of Infectious Diseases, Wright-Patterson Air Force Base, Dayton, Ohio, 45433-5529, USA. peter.ender@wpafb.af.mil |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bartonella
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isolation & purification* Bartonella Infections / complications*, epidemiology Case-Control Studies Coronary Angiography Coronary Disease / etiology*, microbiology Coxiella burnetii / isolation & purification* Cross-Sectional Studies Female Humans Logistic Models Male Odds Ratio Ohio / epidemiology Prospective Studies Q Fever / complications*, epidemiology Risk Factors Seroepidemiologic Studies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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