Document Detail


Associated autoimmune diseases in myasthenia gravis. A population-based study.
MedLine Citation:
PMID:  7793234     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During a comprehensive epidemiological study of myasthenia gravis (MG) in Western Denmark 1975-1989, we analyzed the occurrence, clinical characteristics and prognosis of associated autoimmune diseases (AAD) in MG patients. AAD were found in 20 of 212 incident cases (9%) and in 30 of 220 prevalent cases (14%). The most common diseases were: thyroid disorders and rheumatic arthritis. Clinically, it was not possible to identify a subgroup of MG patients with a higher risk of AAD. In most MG patients the AAD occurred before thymectomy. The severity of the AAD was not influenced by thymectomy. The remission rate was lower in MG patients with AAD than in MG patients without AAD suggesting that the autoimmune response in MG patients with AAD is more severe.
Authors:
P B Christensen; T S Jensen; I Tsiropoulos; T Sørensen; M Kjaer; E Højer-Pedersen; M J Rasmussen; E Lehfeldt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  91     ISSN:  0001-6314     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  1995 Mar 
Date Detail:
Created Date:  1995-07-27     Completed Date:  1995-07-27     Revised Date:  2006-08-16    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  192-5     Citation Subset:  IM    
Affiliation:
Department of Neurology, Aarhus University Hospital, Denmark.
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MeSH Terms
Descriptor/Qualifier:
Arthritis, Rheumatoid / complications*,  epidemiology
Denmark / epidemiology
Female
Humans
Male
Middle Aged
Myasthenia Gravis / complications*,  epidemiology
Prevalence
Prognosis
Retrospective Studies
Severity of Illness Index
Thymectomy
Thymoma / complications*,  epidemiology,  surgery
Thymus Neoplasms / complications*,  epidemiology,  surgery
Thyroid Diseases / complications*,  epidemiology
Comments/Corrections
Comment In:
Acta Neurol Scand. 1995 Dec;92(6):503-4   [PMID:  8750118 ]

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