Document Detail


Assisted reproductive technology in Europe, 2006: results generated from European registers by ESHRE.
MedLine Citation:
PMID:  20570973     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: In this 10th European IVF-monitoring (EIM) report, the results of assisted reproductive techniques from treatments initiated in Europe during 2006 are presented. Data were mainly collected from existing national registers.
METHODS: From 32 countries, 998 clinics reported 458 759 treatment cycles including: IVF (117 318), ICSI (232 844), frozen embryo replacement (FER, 86 059), egg donation (ED, 12 685), preimplantation genetic diagnosis/screening (6561), in vitro maturation (247) and frozen oocytes replacements (3498). Overall this represents a 9.7% increase in activity since 2005, which is partly due to an increase in registers (seven more countries with complete coverage). European data on intrauterine insemination using husband/partner's (IUI-H) and donor (IUI-D) semen were reported from 22 countries. A total of 134 261 IUI-H and 24 339 IUI-D cycles were included.
RESULTS: In 20 countries, where all clinics reported to the IVF register, a total of 359 110 assisted reproductive technology (ART) cycles were performed in a population of 422.5 million, corresponding to 850 cycles per million inhabitants. For IVF, the clinical pregnancy rates per aspiration and per transfer were 29.0 and 32.4%, respectively. For ICSI, the corresponding rates were 29.9 and 33.0%. After IUI-H the delivery rate was 9.2% in women below 40. After IVF and ICSI the distribution of transfer of one, two, three and four or more embryos was 22.1, 57.3, 19.0 and 1.6%, respectively. Compared with 2005, fewer embryos were replaced per transfer, but significant national differences in practice were apparent. The proportion of singleton, twin and triplet deliveries after IVF and ICSI combined was 79.2, 19.9 and 0.9%, respectively. This gives a total multiple delivery rates of 20.8% compared with 21.8% in 2005 and 22.7% in 2004. IUI-H in women below 40 years of age resulted in 10.6% twin and 0.6% triplet pregnancies.
CONCLUSIONS: Compared with previous years, the reported number of ART cycles in Europe has increased, pregnancy rates have increased marginally, even though fewer embryos were transferred and the multiple delivery rates have declined.
Authors:
J de Mouzon; V Goossens; S Bhattacharya; J A Castilla; A P Ferraretti; V Korsak; M Kupka; K G Nygren; A Nyboe Andersen;
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Publication Detail:
Type:  Journal Article     Date:  2010-06-22
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  25     ISSN:  1460-2350     ISO Abbreviation:  Hum. Reprod.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-21     Completed Date:  2010-11-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  England    
Other Details:
Languages:  eng     Pagination:  1851-62     Citation Subset:  IM    
Affiliation:
ESHRE Central Office, Meerstraat 60, B-1852 Grimbergen, Belgium. jacques.demouzon@inserm.fr
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Distribution
Embryo Transfer / statistics & numerical data
Europe / epidemiology
Female
Fertilization in Vitro / statistics & numerical data
Humans
Oocyte Donation / statistics & numerical data
Pregnancy
Pregnancy Rate
Preimplantation Diagnosis / statistics & numerical data
Registries
Reproductive Techniques, Assisted / adverse effects,  statistics & numerical data*
Risk Factors
Investigator
Investigator/Affiliation:
Orion Glozheni / ; Heinz Strohmer / ; Kris Bogaerts / ; Stanimir Kyurkchiev / ; Michael Pelekanos / ; Karel Rezabek / ; Karin Erb / ; Mika Gissler / ; Jacques de Mouzon / ; Taraneh Shojaei / ; Klaus Buhler / ; Basil Tarlatzis / ; G Kosztolanyi / ; H Bjorgvinsson / ; Edgar Mocanu / ; Guilia Scaravelli / ; Voldemars Lejins / ; Zivile Gudleviciene / ; Slobodan Lazarevski / ; Tatjana Motrenko Simic / ; Cornelis Lambalk / ; Johan T Hazekamp / ; Waldemar Kuczynski / ; Carlos Calhaz-Jorge /

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