Document Detail


Assisted reproduction for the validation of gestational age assessment methods.
MedLine Citation:
PMID:  21316308     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Despite major achievements in medicine, preterm birth (PTB) remains a leading cause of infant morbidity and mortality, worldwide. Research efforts have been devoted towards a better understanding of the multifactorial aetiology of PTB and its subtypes, with the purpose of prevention and control. The availability of valid and reliable gestational age data is a prerequisite for PTB classification. Pregnancies conceived through assisted reproduction treatments provide an opportunity for the exact determination of gestational age using date of delivery and dates of fertilization or implantation. The purpose of this review article is to evaluate the current evidence for or against the various methods that can be applied to measure gestational age, namely the first day of the last menstrual period, ultrasound before 20weeks of gestation and post-natal assessments, and to propose the use of assisted reproduction treatments populations for further validation of these methods. Despite major achievements in medicine, preterm birth (PTB) remains a leading cause of infant morbidity and mortality, worldwide. Research efforts have been devoted towards a better understanding of the multifactorial aetiology of PTB and its subtypes, with the purpose of prevention and control. The availability of valid and reliable gestational age data is a prerequisite for PTB classification. Pregnancies conceived through assisted reproduction treatments provide an opportunity for the exact determination of gestational age using date of delivery and dates of fertilization or implantation. The purpose of this review article is to evaluate the current evidence for or against the various methods that can be applied to measure gestational age, namely the first day of the last menstrual period, ultrasound before 20weeks of gestation and postnatal assessments, and to propose the use of assisted reproduction populations for further validation of these methods.
Authors:
Hind Beydoun; Bethrand Ugwu; Sergio Oehninger
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-12-13
Journal Detail:
Title:  Reproductive biomedicine online     Volume:  -     ISSN:  1472-6491     ISO Abbreviation:  -     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2011-2-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101122473     Medline TA:  Reprod Biomed Online     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2010 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Graduate Program in Public Health, Eastern Virginia Medical School, Norfolk, VA, USA.
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