Document Detail

Assisted reproduction in a patient with Klippel-Trenaunay syndrome: management of thrombophilia and consumptive coagulopathy.
MedLine Citation:
PMID:  21188495     Owner:  NLM     Status:  MEDLINE    
Klippel-Trenaunay Syndrome (KTS) is a rare, sporadic triad of congenital malformations involving an extensive port wine stain, soft tissue or bone hypertrophy and underlying venous and/or lymphatic malformation involving an extremity. Pregnancy is known to exacerbate KTS complications and can put women at increased obstetrical risk due to deep venous thrombosis and other thromboembolic events. Here we report a case of a patient with KTS who achieved a pregnancy through in vitro fertilization (IVF) using her own eggs and a gestational surrogate in the setting of hypercoagulability and chronic consumptive coagulopathy.
J Ryan Martin; Salley G Pels; Michael Paidas; Emre Seli
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-12-29
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  28     ISSN:  1573-7330     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-04-27     Completed Date:  2011-08-11     Revised Date:  2013-07-03    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  217-9     Citation Subset:  IM    
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520-8063, USA.
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MeSH Terms
Disseminated Intravascular Coagulation / pathology*
Fertilization in Vitro / methods*
Klippel-Trenaunay-Weber Syndrome / pathology*
Pregnancy Complications
Pregnancy Outcome
Surrogate Mothers
Thrombophilia / pathology*

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